Gianotti Crosti syndrome

Clinic

• Also known as infantile papular acrodermatitis and papulovesicular acrolocated syndrome
• It is a reaction of the skin to a viral infection such asHBV and EBV and other viruses such as HAV, HCV, CMV, CXA, CXA, ADV, RBL, PIV, HIV, Enterovirus and Rotavirus

Presentation

• It is generally recognized as a papular or papulovesicular skin rash occurring mainly on the face and distal aspects of the four limbs.
• Purpura is generally not seen but may develop upon tourniquet test. However, extensive purpura without any hemorrhagic disorder has been reported.
• The presence of less florid lesions on the trunk does not exclude the diagnosis.
• Lymphadenopathy and hepatomegaly are sometimes noted. Raised AST and ALT levels with no rise in conjugated and unconjugated bilirubin levels are sometimes detectable, although the absence of such does not exclude the diagnosis.