View source for PERM, Progressive encephalomyelitis with rigidity and myoclonus entities

=== Clinic ===
PERM is a rare and severe neurological syndrome characterized by '''muscular rigidity''' and '''spasms''' as well as brain stem and '''autonomic dysfunction'''. 

It can be associated with anti-GAD, GlyR, and DPPX antibodies. 

All of these autoantibodies may be variably associated with malignant tumors and their response to immunotherapy, as well as to tumor removal, is not easily predictable.

=== Miasms ===

* Myoclonous, Rigidity
* Autonomic dysfunction
* Myelitis, Multiple sclerosis

[[HTLV-1, Human T lymphotropic virus type 1|HTLV-1]]