View source for WNE, West Nile Encephalitis

=== kkkClinic ===
* It is a [[Viral miasms|viral miasm]]
* In 80%, it show no symptoms and mostly recover completely, though Fatigue / Weakness may last for Weeks / Months.
*Symptoms may range from fever to paralysis and [[meningitis]].
*Sever infection can rarely cause permanent brain damage.
*The most common neuromuscular manifestation is a poliomyelitis syndrome with or without [[Brainstem|brain-stem]] involvement (Respiratory failure)
*Significant neurological deficits are <ref>Hart, J., Tillman, G., Kraut, M.A. ''et al.'' West Nile virus neuroinvasive disease: neurological manifestations and prospective longitudinal outcomes. ''BMC Infect Dis'' '''14''', 248 (2014). <nowiki>https://doi.org/10.1186/1471-2334-14-248</nowiki></ref>
**49% Weakness
**35% Tremor 
**16% Cranial neuropathy


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|Poliomyelitis <ref name=":0">A Wolf in Sheep’s Clothing: West Nile Virus presenting as Guillain Barre Variant (P11-9.005)

Subhan Tabba, Asif Kabani

Neurology May 2022, 98 (18 Supplement) 3438;</ref>
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* [[LMN, Lower Motor Neuron|LMN]]
* Asymmetrical [[Flaccid Paralysis miasms|flaccid Paralysis]] (Monoparesis, [[Hemiparesis miasms|Hemiparesis]], Quadriparesis)
|[[GBS, Guillian Barre syndrome|GBS]] <ref name=":0" />
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|[[Encephalitis]]
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*Mild confusion / Deep coma
*Behavioral changes (Like [[Hysteria remedies|Hysteria]])
*[[Seizure|Convulsions]] <ref>https://www.encephalitis.info/</ref> 
*[[Depression]] <ref>Paul J. Carson, Patrick Konewko, Kimberly S. Wold, Paul Mariani, Sunil Goli, Paula Bergloff, Ross D. Crosby, Long-Term Clinical and Neuropsychological Outcomes of West Nile Virus Infection, ''Clinical Infectious Diseases'', Volume 43, Issue 6, 15 September 2006, Pages 723–730,</ref>
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|Myositis  
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|[[Polyradiculitis]] 
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|[[Brachial plexus neuropathy|Brachial plexopathy]] <ref name=":2">Madden K. West Nile virus infection and its neurological manifestations. Clin Med Res. 2003 Apr;1(2):145-50. doi: 10.3121/cmr.1.2.145. PMID: 15931302; PMCID: PMC1069038.</ref>
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* Spinal sympathetic ganglianopathy (Autonomic instability) <ref>Budhram A, Sharma M, Shettar B, Hosseini-Moghaddam SM, Khaw AV. Sensory and autonomic involvement in West Nile virus-associated acute flaccid paralysis. Neurol Clin Pract. 2017 Oct;7(5):394-397. doi: 10.1212/CPJ.0000000000000373. PMID: 29620087; PMCID: PMC5874468.</ref>
|Rapid pulse, Flushed Face, Coldness of feet)
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* [[Parkinsonism]] 
** [[Tremor]] (35%)
** Bradykinesia
** [[Rigidity]] / [[Spasm]]  / Stiffness
**[[Ataxia]] /Postural instability
* [[Meningitis]]: Headache; retro-orbital
* [[Optic neuritis]]



* [[Pharyngitis]]: Rawness, Sore throat, Cervical lymphadenopathy
* [[Myocarditis]]: Palpitation

* Splenomegaly: Leukopenia
* [[Hepatitis]]: Hepatomegaly,  Nausea, Vomiting, Loss of appetite, and Diarrhea
* [[Pancreatitis]]: Diarrhea

* Eruptions: maculopapular, pale roseolar
*Hyponatremia
*Lying in bed agg. Night agg
*Eye Pain. Injected



=== WNND ===

* '''W'''est '''N'''ile '''N'''euroinvasive '''D'''isease occurs in less than 1% of cases, resulting in meningitis, encephalitis, [[Meningoencephalitis remedies|meningoencephalitis]] or a poliomyelitis-like syndrome.
* Often there is normal neuroimaging, although abnormalities including basal ganglia, thalamus, cerebellum, and brain-stem have been reported
* Muscular weakness + [[LMN, Lower Motor Neuron|Lower motor neuron symptoms]], Flaccid paralysis, + Hyporeflexia +No sensory abnormalities.<ref name=":3">Wikipedia</ref>


=== WNP ===

* '''W'''est '''N'''ile '''P'''oliomyelitis is an acute flaccid paralysis syndrome associated with WNV
*It is less common than WNM or WNE. 
*It is generally characterized by the acute onset of Asymmetric limb weakness or paralysis in the absence of sensory loss.
*Pain sometimes precedes the paralysis. The paralysis can occur in the absence of fever, headache, or other common symptoms associated with WNV infection. 
*Involvement of respiratory muscles, leading to acute respiratory failure, sometimes occurs.
* West-Nile reversible paralysis, Like WNP, the weakness or paralysis is asymmetric. Reported cases have been noted to have an initial preservation of deep tendon reflexes, which is not expected for a pure anterior horn involvement. 
*Disconnect of upper motor neuron influences on the anterior horn cells possibly by myelitis or glutamate excitotoxicity have been suggested as mechanisms.<ref name=":3" />

* Typical WNE paralysis is characterized by muscle weakness, decreased tone, and loss of deep tendon reflexes attributed to destruction of anterior horn cells.<ref>Mojumder DK, Agosto M, Wilms H, Kim J. Is initial preservation of deep tendon reflexes in West Nile Virus paralysis a good prognostic sign? Neurol Asia. 2014 Mar;19(1):93-97. PMID: 25400704; PMCID: PMC4229851.</ref> 


=== Disease ===

* [[Myasthenia gravis]]
* [[Stiff person syndrome|Stiff-person syndrome]] <ref name=":1">REVIEW article

Front. Neurol., 21 March 2012

Sec. Neuromuscular Disorders and Peripheral Neuropathies

<nowiki>https://doi.org/10.3389/fneur.2012.00037</nowiki></ref>
*[[Parkinson disease]]



=== [[Homeopathic remedies|Remedies]] ===
#
# '''[[Iod, Iodium|IOD]], [[Merc, Mercurius Solubilis|MERC]].''' '''PHOS'''
# Bell, Caust.  Cupr. Plb. Sil. Sulph.
# agar, aur. Calc con gels kali-c


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