Role of serotonin in IBS: Revision history

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23 March 2023

2 November 2022

  • curprev 09:0209:02, 2 November 2022Oldver>Mehrdad 1,820 bytes +1,820 Created page with "Serotonin (5-HT) is an important signaling molecule in the gut targeting enterocytes, smooth muscles and enteric neurons. Most of the body serotonin is present in enterochromaffin cells. Serotonin activates both intrinsic and extrinsic primary afferent neurons to, respectively initiate peristaltic and secretory reflexes and to transmit information to the central nervous system. Serotonin is inactivated by the serotonin reuptake transporter (SERT) in the enterocytes or ne..."