Ataxia: Difference between revisions

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=== Clinic ===
=== Clinic ===


* Recently Ataxia is used specifically to describe the symptoms of motor mismatching synchronization and balance disorder after the brain, cerebellum, deep sensation ([[proprioception]]), vestibular and other systems are damaged
* Recently Ataxia is used specifically to describe the symptoms of motor mismatching synchronization and balance disorder due to disorders of Brain, Cerebellum, Deep sensation ([[proprioception]]) and Vestibular system.
* Different pathological locations often show different characteristics.  
* Different pathological locations often show different characteristics.  
** Sensory ataxia is caused by the impairment of somatosensory nerve, which leads to the interruption of sensory feedback signals and therefore, the body incoordination is caused.  
** Sensory ataxia: Impairment of somatosensory nerve, which leads to the interruption of sensory feedback signals and therefore, the body incoordination is caused.
** Cerebellar Ataxia has Romberg’s sign means that slow Walking / Rolling become mild when eyes are open and aggravated when eyes are closed. It is caused by cerebellar disease.  
** Cerebellar Ataxia: Positive Romberg’s sign means that slow Walking / Rolling become mild when eyes are open and aggravated when eyes are closed.  
** Trunk ataxia often indicates cerebellar vermis lesions
** Trunk ataxia: Often Cerebellar vermis is involved.
** Limb ataxia often indicates cerebellar hemisphere lesions. The corresponding patients often have eye tremor, low muscle tension, unclear speech, and other symptoms
** Limb ataxia: Often cerebellar hemisphere is involved. The corresponding patients often have eye tremor, low muscle tension, unclear speech, and other symptoms
* Ataxia is a [[Cluster of disease|COD]], since it has a variety of Sigh / Symptoms which have a common axis, which is named cerebellum. These Sign / Symptoms arise from different pars of cerebellum and their extra cerebellar centers. As I explained it in more details in [[Nerocognitive considerations]], Ultra complexity of our nervous system does not let neuroscientists to localized Functional units Anatomically  / Physiologically. Although it is very Tempting to isolate the functional units of nervous system, But we are not allowed to delay the treatment of patients until these physiological units are isolated. So TLT tries to make a model by use these functional units only by their function and dysfunction. Here is the list of Ataxia entities:
* Ataxia is a [[Cluster of disease|COD]], since it has a variety of Sigh / Symptoms which have a common axis, which is named cerebellum. These Sign / Symptoms arise from different pars of cerebellum and their extra cerebellar centers. As I explained it in more details in [[Nerocognitive considerations]], Ultra complexity of our nervous system does not let neuroscientists to localized Functional units Anatomically  / Physiologically. Although it is very Tempting to isolate the functional units of nervous system, But we are not allowed to delay the treatment of patients until these physiological units are isolated. So TLT tries to make a model by use these functional units only by their function and dysfunction. Here is the list of Ataxia entities:
** Dysarthria
** Dysarthria
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==== Clinic ====
==== Clinic ====
*Sensory Ataxia is a form of ataxia caused '''not''' by cerebellar dysfunction  
*Sensory Ataxia is a form of ataxia caused '''not''' by cerebellar dysfunction. It is due to
*It is due to  
**Loss of Sensory input / [[Proprioception]]
**Loss of Sensory input / Proprioception (Positions of joint and body parts)
**Dysfunction of dorsal columns of spinal cord (Carry proprioceptive information)
**Dysfunction of dorsal columns of spinal cord (Because they carry proprioceptive information up to brain)
**Dysfunction of various parts of brain that receive positional information, including the cerebellum, thalamus and parietal lobes.
**Dysfunction of the various parts of the brain that receive positional information, including the cerebellum, thalamus, and parietal lobes.




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=== '''[[Acute cerebellar ataxia of childhood]]''' ===
=== '''[[Acute cerebellar ataxia of childhood]]''' ===
So there are three interactive system involved in Ataxia:
# Propioceptive system
# Visual / Vestibular system
# Central system
=== Vestibular ataxia ===
* There are two kind of vertigo, True and not true.
*# True vertigo has turning sensation weather he is turning around others or others turns around him.
*# False vertigo simply dose not have turning sensation. He has Unsteadiness or Dizziness
* False vertigo: The patient has Dizziness NOT true vertigo: Ataxia + Unsteadiness: STLE
==== Vestibular ataxia with true vertigo ====
{| class="wikitable"
!True vertigo
!
!VZV
!RBOL
!MMP
!RSV
|-
| rowspan="2" |Sensory (Rhomberg Neg + True vertigo With/Without Ear problems):
* Vertigo
* Ataxia
* Labyrantitis  OR Vestibular Neuritis
|Labyrantitis
(Ear problems)
| +++
| +++
|
| +
|-
|Vestibular Neuritis
(NO Ear problems)
| +++
| +++
|
|
|-
| rowspan="2" |Cerebellar (Rhomberg Pos + True vertigo With/Without Ear problems):
* Vertigo
* Ataxia
* Labyaintitis  OR Vestibular Neuritis
|Labyrantitis
(Ear problems)
| +++
| +++
| +++
|
|-
|Vestibular Neuritis
(NO Ear problems)
| +++
| +++
| +++
|
|}
=== Propioceptive ataxia ===
* [[Proprioception]] is disordered. Considering Rhomberg test and Lower or Upper extremities, I suggest these miasms as fallow:
==== Propioceptive ataxia ====
{| class="wikitable"
!Propioceptive ataxia
!
!GSS
!CXA
!CJD
!VZV
!MMP
!TBE
!KRU
!STLE
!SHBV
|-
| rowspan="3" |Sensory (Rhomberg Neg)
|Lower ext
|
|
| +++
|
|
|
|
|
|
|-
|Upper ext
| +++
| +++
|
| +++
|
| +++
|
|
|
|-
|Both ext
|
|
|
|
|
|
|
| +++
| +++
|-
| rowspan="2" |Cerebellar (Rhomberg Pos)
|Lower ext
|
|
| +++
|
|
|
|
|
|
|-
|Upper ext
| +++
| +++
|
| +++
| +++
|
| +++
|
|
|}

Revision as of 05:16, 15 April 2023

Clinic

  • Recently Ataxia is used specifically to describe the symptoms of motor mismatching synchronization and balance disorder due to disorders of Brain, Cerebellum, Deep sensation (proprioception) and Vestibular system.
  • Different pathological locations often show different characteristics.
    • Sensory ataxia: Impairment of somatosensory nerve, which leads to the interruption of sensory feedback signals and therefore, the body incoordination is caused.
    • Cerebellar Ataxia: Positive Romberg’s sign means that slow Walking / Rolling become mild when eyes are open and aggravated when eyes are closed.
    • Trunk ataxia: Often Cerebellar vermis is involved.
    • Limb ataxia: Often cerebellar hemisphere is involved. The corresponding patients often have eye tremor, low muscle tension, unclear speech, and other symptoms
  • Ataxia is a COD, since it has a variety of Sigh / Symptoms which have a common axis, which is named cerebellum. These Sign / Symptoms arise from different pars of cerebellum and their extra cerebellar centers. As I explained it in more details in Nerocognitive considerations, Ultra complexity of our nervous system does not let neuroscientists to localized Functional units Anatomically / Physiologically. Although it is very Tempting to isolate the functional units of nervous system, But we are not allowed to delay the treatment of patients until these physiological units are isolated. So TLT tries to make a model by use these functional units only by their function and dysfunction. Here is the list of Ataxia entities:
    • Dysarthria
    • Gait abnormality: Balance disturbances
    • Vertigo: Postural instability
    • Unsteadiness
    • Ext, Incoordination: Dysdiadochokinesia, Dysmetria, Peculiar writing abnormalities
    • Ext, Awkwardness
    • Nystagmus
    • Tremor
  • Lack of voluntary coordination of muscle movements that can include gait abnormality, speech changes, and abnormalities in eye movements.
  • Ataxia can be limited to one side of the body, which is referred to as hemiataxia.
  • Dystaxia is a mild degree of ataxia.

Here we have a confusing rubric, named Ataxia. Since it is used in its general them, means unbalance movements. I prefer using this rubric as a general guiding in all problems of Balance system, But for finding one or two miasm, you should add an entity to it.

Types

Cerebellar ataxia

Dysfunction of the cerebrocerebellum

(Lateral hemispheres) Appendicular ataxia

Intention tremor

Coarse trembling

Accentuated over the execution of voluntary movements

Possibly involving head, eyes, limbs and torso

Peculiar writing abnormalities

Large, unequal letters

Irregular underlining

Peculiar Dysarthria

Slurred speech

characterized by explosive variations in voice intensity despite a regular rhythm

Dysdiadochokinesia

Inability to perform rapidly alternating movements which could involve rapidly switching from pronation to supination of the forearm.

Movements become more irregular with increases of speed.

Dysmetria

Hypometria or overshooting Hypermetria


Inability to judge distances or ranges of movement happens.

Rebound phenomenon

Loss of the check reflex

Schmahmann's syndrome

Patients may exhibit a constellation of subtle to overt cognitive symptoms

Dysfunction of the spinocerebellum

(Vermis and areas near the midline)

Truncal ataxia:
  • Uncertain starts and stops
  • Lateral deviations
  • Unequal steps
Vestibulocerebellum dysfunction

Flocculonodular lobe

  • Balance disturbances
  • Control of eye movements
  • Postural instability
  • Negative Romberg's test


Sensory Ataxia

Clinic

  • Sensory Ataxia is a form of ataxia caused not by cerebellar dysfunction. It is due to
    • Loss of Sensory input / Proprioception
    • Dysfunction of dorsal columns of spinal cord (Carry proprioceptive information)
    • Dysfunction of various parts of brain that receive positional information, including the cerebellum, thalamus and parietal lobes.



Vestibular Ataxia

  • Ataxia due to dysfunction of the vestibular system
  • Acute and unilateral cases is associated with prominent vertigo, nausea, and vomiting.
  • In chronic bilateral cases, dysequilibrium may be the only presentation.

Bilateral vestibular hypofunction

Spinocerebellar ataxia

Vestibulocerebellar ataxia

Truncal ataxia

Truncal ataxia is caused by midline damage to the cerebellar vermis.

Acute cerebellar ataxia of childhood

So there are three interactive system involved in Ataxia:

  1. Propioceptive system
  2. Visual / Vestibular system
  3. Central system

Vestibular ataxia

  • There are two kind of vertigo, True and not true.
    1. True vertigo has turning sensation weather he is turning around others or others turns around him.
    2. False vertigo simply dose not have turning sensation. He has Unsteadiness or Dizziness
  • False vertigo: The patient has Dizziness NOT true vertigo: Ataxia + Unsteadiness: STLE

Vestibular ataxia with true vertigo

True vertigo VZV RBOL MMP RSV
Sensory (Rhomberg Neg + True vertigo With/Without Ear problems):
  • Vertigo
  • Ataxia
  • Labyrantitis OR Vestibular Neuritis
Labyrantitis

(Ear problems)

+++ +++ +
Vestibular Neuritis

(NO Ear problems)

+++ +++
Cerebellar (Rhomberg Pos + True vertigo With/Without Ear problems):
  • Vertigo
  • Ataxia
  • Labyaintitis OR Vestibular Neuritis
Labyrantitis

(Ear problems)

+++ +++ +++
Vestibular Neuritis

(NO Ear problems)

+++ +++ +++

Propioceptive ataxia

  • Proprioception is disordered. Considering Rhomberg test and Lower or Upper extremities, I suggest these miasms as fallow:

Propioceptive ataxia

Propioceptive ataxia GSS CXA CJD VZV MMP TBE KRU STLE SHBV
Sensory (Rhomberg Neg) Lower ext +++
Upper ext +++ +++ +++ +++
Both ext +++ +++
Cerebellar (Rhomberg Pos) Lower ext +++
Upper ext +++ +++ +++ +++ +++