TMEV, Theiler murine encephalomyelitis virus

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  • TMEV is a single-stranded RNA murine cardiovirus from the family Picornaviridae.
  • It has been used as a mouse model for studying virally induced paralysis, as well as encephalomyelitis comparable to multiple sclerosis.
  • Depending on the mouse and viral strain, viral pathogenesis can range from negligible, to chronic or acute encephalomyelitis.
  • TMEV could be used as an animal model of Experimental autoimmune encephalomyelitis.
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