Generalized anxiety disorder

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Revision as of 10:33, 18 April 2023 by Mehrdad (talk | contribs) (Created page with "=== Clinic === * GAD is a mental and behavioral disorder * It is characterized by excessive, uncontrollable and often irrational worry about events /activities. * Worry often interferes with daily functioning, and individuals with GAD are often overly concerned about everyday matters such as health, finances, death, family, relationship concerns, or work difficulties. * Symptoms may include excessive worry, restlessness, trouble sleeping, exhaustion, irritability, swea...")
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Clinic

  • GAD is a mental and behavioral disorder
  • It is characterized by excessive, uncontrollable and often irrational worry about events /activities.
  • Worry often interferes with daily functioning, and individuals with GAD are often overly concerned about everyday matters such as health, finances, death, family, relationship concerns, or work difficulties.
  • Symptoms may include excessive worry, restlessness, trouble sleeping, exhaustion, irritability, sweating, and trembling.


Symp/ Parasympathetic dysregulations
General Local
ParaSympathetic over activity Sympathetic over activity
  • Bradycardia
  • Dizziness, unsteady, faint or light-heat
  • Depression
  • Tachycardia
  • Sweating
  • Trembling / Shaking
  • Anxiety / Fears
  • Restlessness / Excitability / Startling / Irritability
  • Difficulty in concentrating
  • Derealization or Depersonalization
  • Dry mouth
  • Difficulty breathing
  • Feeling of choking
  • Chest pain or discomfort
  • Nausea or abdominal distress
  • Hot flashes or cold chills
  • Numbness or tingling sensations
  • Muscle tension or aches and pains
  • Throat lump sensation or difficulty in swallowing

Related disease

  • Major depressive disorder: There is a strong overlapping relationship between GAD and MDD (72%)
  • Substance use disorder
  • Obesity


Pathphysiology

  • The pathophysiology of GAD implicates several regions of the brain that mediate the processing of stimuli associated with fear, anxiety, memory, and emotion (i.e., the amygdala, insula and the frontal cortex).
  • GAD have greater amygdala and medial prefrontal cortex (mPFC) activity in response to stimuli than individuals who do not have GAD. However, the relationship between GAD and activity levels in other parts of the frontal cortex is the subject of ongoing research with some literature suggesting greater activation in specific regions for individuals who have GAD but where other research suggests decreased activation levels in individuals who have GAD as compared to individuals who do not have GAD.


Entities / Miasm

As I said before, I consider syncope as a good Cluster of entities for Dysautonomia

Therefore RBS and TBE are highly suggested

GAD entities RBS PLV VZV TBE DHF
Anxiety/ Fear/ Excitability/ Restlessness ++ +++ ++ ++ ++
Insomnia + +
Increased perspiration +++ +++
Sympathetic Hyperactivity +++ ???
Paresthesia +++ ++ + ++
Fear of dying + +
Throat Chocking/ Lump +++
Ileus +++ +++ ++
Urine incontinence ??? +++
Feet coldness

Face flashed

+++ +++
GAD miasms
Miasms General

ParaSympathetic

over activity

General

Sympathetic

over activity

Mind Skin

Mucous membranes

Perspiration

Genitourinary GI Throat

Mouth

Ext
SAHF Hypotention orthostatic

Bradycardia

Dizziness



Depression

Anxiety

Flashed (Face, Eye, Chest)

Hyperstasia



Constipation Mouth dryness Tremor
RBS

Dilated pupil

Tachycardia

Bradycardia

Anxiety

Excitability / Fear

Impaired concentration

Paresthesia

Sweating


Anorexia

Diarrhea

Ileus

Choking sensation
VZV
Tachycardia Anxiety

Excitability

Impaired concentration

Paresthesia

Flushed face

Involuntary urine Anorexia

Diarrhea

Ileus


Coldness
DHF
Tachycardia Anxiety

Excitability

Hyperstasia

Sweating


Anorexia Mouth dryness Coldness
HSV Hypotention orthostatic

Fatigue

Tachycardia Excitability Paresthesia

Hyperstasia

Involuntary urine

Urgency

Retention

Male impotence

Anorexia

Constipation

Involuntary stool

Diarrhea

Dysphagia


Coldness
CMV Hypotention orthostatic

Fatigue

Tachycardia
Paresthesia

Sweating

Involuntary urine Anorexia

Involuntary stool

Diarrhea

Ileus

Dysphagia


Coldness