Necrotizing enterocolitis

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Clinic

  • NEC is a devastating intestinal disease that affects premature or very low birth weight infants.
  • Initial symptoms include
    • Feeding intolerance and failure to thrive
    • Increased gastric residuals
    • Abdominal distension
    • Bloody stools.
  • Symptoms may progress rapidly to abdominal discoloration with intestinal perforation and peritonitis and systemic hypotension requiring intensive medical support.

Main risk factors

  • Low birth weight / Prematurity
  • Formula feeding (bovine based)
  • Intestinal dysbiosis

Pathophysiology

  • Combination of poor blood flow and intestinal infection
  • 7% of those who are born prematurely develop NEC

Diagnostic feature

  • Intestinal pneumatosis, Pneumatosis cystoides intestinalis, Pneumatosis coli, or Intramural bowel gas
  • It is gas cysts in the bowel wall.
  • It is As a radiological sign of necrotizing enterocolitis.

Miasm

RTV