Parkinson's disease dementia
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Clinic
- PDD is dementia that is associated with Parkinson's disease (PD).
- Together with dementia with Lewy bodies (DLB), it is one of the Lewy body dementias characterized by abnormal deposits of Lewy bodies in the brain.
- PD starts as a movement disorder, but progresses in most cases to include dementia, and changes in mood and behavior.
- The signs, symptoms and cognitive profile of PDD are similar to those of DLB
- DLB and PDD are clinically similar after dementia occurs in Parkinson's disease.
- PD is a risk factor for PDD; it speeds up decline in cognition leading to PDD.
- Up to 78% of people with PD have dementia.
PDD vs DBL
| PDD | DBL | |
|---|---|---|
| Visual hallucinations | Less | More |
| Tremor | More | Less |
| Parkinsonism | Symmetric | Asymmetric |
| Delusions | Less | More |
| JE | CJD | ||
|---|---|---|---|
| Parkinsonism | +++ | +++ | |
| Dementia | +++ | +++ | |
| Psychosis | +++ | +++ |