Spinocerebellar ataxia

Clinic

• SCA is a progressive, degenerative, genetic disease with multiple types, each of which could be considered a neurological condition in its own right.
• SCA is hereditary, progressive, degenerative, and often fatal.
• Hereditary ataxias can be inherited in an autosomal dominant, autosomal recessive, or X-linked manner.

Signs / Symptoms

• Slowly progressive incoordination of gait
• Poor coordination of hands,
• Poor coordination of speech,
• Poor coordination of eye movements
• Non-cerebellar features are
• Parkinsonism,
• Chorea
• Pyramidalism
• Cognitive impairment
• Peripheral neuropathy
• Seizures

Cause[edit]

The hereditary ataxias are categorized by mode of inheritance and causative gene or chromosomal locus. The^{itation needed]}