Erythema multiforme
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Clinic
- EM is a skin condition that appears with red patches evolving into target lesions, typically on both hands.
- It is a type of erythema possibly mediated by deposition of immune complexes in the superficial microvasculature of the skin and oral mucous membrane
Causes
- Bacterial ( Bacillus Calmette–Guérin (BCG) vaccination, haemolytic Streptococci, legionellosis, leprosy, Neisseria meningitidis, Mycobacterium, Pneumococcus, Salmonella species, Staphylococcus species, Mycoplasma pneumoniae(More common), chlamydial.
- Fungal (Coccidioides immitis)
- Parasitic (Trichomonas species, Toxoplasma gondii)
- Viral (HSV-1, HSV-2 in 55% of cases)
- Drug reactions
- Physical factors: radiotherapy, cold, sunlight
Related Diseases
- Collagen diseases
- Vasculitides
- Non-Hodgkin lymphoma
- Leukaemia
- Multiple myeloma
- Myeloid metaplasia
- Polycythemia
- Stevens–Johnson syndrome