Acute inflammatory demyelinating polyradiculoneuropathy

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Clinic

  • Acquired acute demyelinating peripheral polyneuropathy (AADP) is a general classification of pathologies that could affect secondary the peripheral nervous system.
  • They are characterized by an autoimmune inflammation of myelin characterized by progressive weakness and mild sensory changes.
  • It is a progressive usually bilateral weakness, hyporeflexia, with a typical demyelinating EMG pattern.
  • Progressive affection of respiratory muscles and autonomic instability may leads to mortality.
  • AIDP has a typical Guillain-Barré syndrome (GBS) presentation but with a unilateral upgoing plantar reflex (Babinski sign /Plantar reflex).



Miasm

GBS

Loss of deep tendon reflex

RBS, CMV