Acute panautonomic neuropathy
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Clinic
- Also called Pandysautonomia, is a rare form of Guillain-Barré syndrome
- It is characterized by parasympathetic and sympathetic failure with minimal or no somatosensory or motor impairment.
- Immune-mediated mechanism usually affect efferent postganglionic sympathetic and parasympathetic pathways.
- Slow, incomplete recovery
- Persistent orthostatic hypotension is common
- No effective therapy is available yet.
Sign / Symptoms
- Gastrointestinal symptoms (Abdominal pain, Vomiting, Constipation, Diarrhea, Gastroparesis, Ileus)
- Orthostatic hypotension
- Erectile dysfunction
- Urinary frequency, urgency or retention
- Vasomotor instability (Also referred to as hot Flashing)
- Acrocyanosis
- Reduced salivation, lacrimation and sweating