Bronchiectasis

Clinic

• It is permanent enlargement of parts of the airways
• The development of bronchiectasis requires two factors:

1. An initial inflammation of lung tissue such as infection or autoimmunity or aspiration syndromes seen in GERD
2. This leads to impaired mucociliary clearance, obstruction, or a defect in host defense. This triggers a host immune response from neutrophils (elastases), reactive oxygen species, and inflammatory cytokines that results in progressive destruction of normal lung architecture.

• In particular, the elastic fibers of bronchi are affected.
• The result is permanent abnormal dilation and destruction of the major bronchi and bronchiole walls

Note

• There is two kind of pathogenesis in Lung tissues, Fibrosis and looseness.
• Intermingling both of them could be due to MTB, Although HCV is also considered in fibrosis.
• Bronchiectasis is an entity composed of inflammation of airways (Large to Medium sized) which lads to looseness of them

Signs and symptoms

• Productive cough (Green or yellow sputum)
• Dyspnea
• Wheezing
• Chest pain
• Hemoptysis.

• Expiratory rhonchi
• Nail clubbing is a rare symptom

Causes

Dynamic	Static
Lung infections: MTB Pneumonia Autoimmune diseases Rheumatoid arthritis Sjögren syndrome Ulcerative colitis Crohn's disease Allergic bronchopulmonary aspergillosis	Cystic fibrosis Chronic aspiration Ammonia inhalation Smoke inhalation Radiation-induced lung disease Yellow nail syndrome Congenital disease Tumor Foreign body aspiration Lymphadenopathy

Tissue Salt Remedies

SIL

Related entities

• Bronchitis
• Pneumonia
• Bronchiolitis

Related Disease

Asthma