Cortical blindness

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Clinic

  • Cortical blindness is the total or partial loss of vision in a normal-appearing eye caused by damage to the brain's occipital cortex
  • Rarely, a patient with acquired cortical blindness may have little or no insight that they have lost vision, a phenomenon known as Anton–Babinski syndrome.
  • Cortical blindness and cortical visual impairment (CVI), which refers to the partial loss of vision caused by cortical damage, are both classified as subsets of neurological visual impairment (NVI).
  • NVI and its three subtypes—cortical blindness, cortical visual impairment, and delayed visual maturation—must be distinguished from ocular visual impairment in terms of their different causes and structural foci, the brain and the eye respectively.
  • One diagnostic marker of this distinction is that the pupils of individuals with cortical blindness will respond to light whereas those of individuals with ocular visual impairment will not.


Symptoms

  • Complete loss of visual sensation and of vision
  • Preservation of the abilities to perceive Light / Moving, but not static objects (Riddoch syndrome)
  • Lack of visual fixation and tracking
  • Denial of visual loss (Anton–Babinski syndrome)
  • Visual hallucinations
  • Macular sparing, in which vision in the fovea is spared from the blindness.

Causes

Static Dynamic
  • Congenital abnormalities of the occipital lobe
  • Occipital lobe trauma
  • Perinatal ischemia
  • Side effect of some anti-epilepsy drugs (AEDs)
  • Hyperammonemia
  • Eclampsia and, rarely, pre-eclampsia
  • Infection
  • CJD, in association with a rapid onset of dementia
  • Encephalitis
  • Meningitis
  • Bilateral lesions of the primary visual cortex
  • Dissociative identity disorder (DID)


DD

Cerebral achromatopsia

Miasms

CJD