Interstitial nephritis

From Wikihomeopathy
Jump to navigation Jump to search

Clinic

  • Also known as tubulointerstitial nephritis
  • It is inflammation of renal interstitium, which consists of a collection of cells, extracellular matrix, and fluid surrounding the renal tubules.
  • Renal interstitium participate in the fluid and electrolyte exchange as well as endocrine functions.


Signs / Symptoms

  • Fever is the most common, occurring in 30-50% of patients, particularly those with drug-induced interstitial nephritis.
  • Nausea, vomiting, fatigue, lack of appetite, and weight loss.
  • Flank pain, Pain with urination
  • Hematuria
  • Hypertension
  • Classic triad of symptoms: Rash + Arthralgia + Eosinophilila (5-10% of patients)


Causes

  • Dynamic: Infection
  • Static: Reaction to drugs such as an analgesic, anti-inflammatory, or antibiotics


Miasm

HFRS