Necrotizing fasciitis

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Clinic

  • NF, also known as flesh-eating disease, is a Skin disease
  • It is a bacterial gangrenous infection of superficial soft tissue
  • Symptoms usually include red or purple skin in the affected area, severe pain, fever, and vomiting
  • The most common affected areas are limbs and perineum.

Signs / Symptoms

  • Fever
  • Swelling
  • Excessive pain
  • It starts with Cellulitis / Abscess like image but in the following days Necrotizing changes occur


Other signs are:

  • Formation of bullae
  • Bleeding
  • Skin turning from red to purple and black due to thrombosis of blood vessels)
  • Presence of gas in tissues
  • Reduced or absent sensation over the skin due to underlying nerves necrosis
  • Rapid progression to shock

Necrotizing changes affecting the groin are known as Fournier gangrene.[2]

Cause

Bacterial

  • Staphylococcus aureus
  • Streptococcus pyogenes
  • Enterococci
  • Escherichia coli
  • Pseudomonas aeruginosa
  • Bacteroides
  • Clostridium species
  • Clostridium perfringens
  • Clostridium septicum
  • Clostridium sordellii


Fungal