Polymyositis

Polymyositis (PM) is a type of inflammatory myopathy related to dermatomyositis and inclusion body myositis.
The hallmark of polymyositis is weakness and/or Atrophy
These symptoms can be associated with marked pain in these areas as well.
The hip extensors are often severely affected, leading to particular difficulty in climbing stairs and rising from a seated position.
Dysphagia or other problems with esophageal motility occur in as many as 1/3 of patients.
Low grade fever and enlarged lymph nodes may be present.
Foot drop in one or both feet can be a symptom of advanced polymyositis and inclusion body myositis.
Systemic involvement of polymyositis includes interstitial lung disease (ILD) and heart disease, such as heart failure and conduction abnormalities.
The weakness is generally progressive, accompanied by lymphocytic inflammation (mainly cytotoxic T cells)

Cancer: Nasopharyngeal cancer, Lung cancer, Non-Hodgkin's lymphoma, Bladder cancer
Interstitial lung disease 65%
Anti-Jo-1 antibody
Cardiac involvement manifests in 77% of patients
Celiac disease

Navigation menu