Rasmussen's encephalitis

Clinic

• RE is a very rare, chronic Autoimmune Inflammation of one hemisphere of brain. 
• It most often occurs in children under the age of 10

Sign / Symptoms

• Frequent / Severe / Partial seizures (Epilepsia Partialis Continua)
• Progressive loss of Motor skills / Speech
• Hemiparesis
• Encephalitis
• Cognitive difficulties (Learning, memory or language)
• Hemianopia: Loss of vision for one side of the visual field

Pathophysiology

• The cause of the inflammation is not known but recent studies report the presence of autoantibodies against the NMDA-type glutamate receptor subunit GluRepsilon2 (anti-NR2A antibodies) in a subset of patients with Rasmussen's encephalitis.

Entities

• Aphasia
• Cognition impaired
• Seizure
• Visual field deficit
• Hemipareisis

Miasms

JE

Related Disease

• Neurovisceral porphyria / Acute intermittent porphyria