TSE, Transmissible spongiform encephalopathy

Clinic

• TSEs are a group of progressive and fatal conditions that are associated with prions and affect the brain and nervous system of many animals

Etiology

• According to the most widespread hypothesis, they are transmitted by prions including
  • CJD
  • GSS
  • FFI
  • KRU

CJD itself has four main forms:

• Sporadic (sCJD)
• Hereditary/familial (fCJD)
• Iatrogenic (iCJD)
• Variant form (vCJD)