Thymus gland

Clinic

• Immunodeficiency: Thymus is the location of T cells development, congenital problems such as DiGeorge syndrome, CHARGE syndrome could results in severe immunodeficiency

• Autoimmune polyendocrine syndrome type 1: APS-1 is a rare genetic autoimmune syndrome that results from a genetic defect of the thymus tissues.

• Thymoma-associated multiorgan autoimmunity: This is because the malignant thymus is incapable of appropriately educating developing thymocytes to eliminate self-reactive T cells.

• Myasthenia gravis

• Cancer: Tumors of the hematopoietic and lymphoid tissues

• Thymomas

• Lymphomas

EBV is associated with Lymphoma and some how to Thymoma.