View source for Anti LGI1 encephalitis

=== Clinic ===
*They have limbic encephalitis with amnesia and/or confusion (100%)
**Up to 13% of patients with LGI1 Abs develop cognitive impairment. <ref>Ariño H, Armangué T, Petit-Pedrol M, Sabater L, Martinez-Hernandez E, Hara M, Lancaster E, Saiz A, Dalmau J, Graus F. Anti-LGI1-associated cognitive impairment: Presentation and long-term outcome. Neurology. 2016 Aug 23;87(8):759-65. doi: 10.1212/WNL.0000000000003009. Epub 2016 Jul 27. PMID: 27466467; PMCID: PMC4999321.</ref> 
*Seizures (84-92%): Tonic seizures with movements of Leg, Arm or Face ([[Faciobrachial dystonic seizure entities|Faciobrachial dystonic seizures]]) <ref>Aurangzeb S, Symmonds M, Knight RK, Kennett R, Wehner T, Irani SR. LGI1-antibody encephalitis is characterised by frequent, multifocal clinical and subclinical seizures. Seizure. 2017 Aug;50:14-17. doi: 10.1016/j.seizure.2017.05.017. Epub 2017 May 30. PMID: 28586706; PMCID: PMC5558811.</ref>
*Hyponatremia (60%)
*Movement disorders ([[Myoclonus entities|Myoclonus]]/ Dyskinesia)
*Sleep disorders (Hypersomnia, insomnia, [[RBD, Rapid Eye Movement Sleep Behavior Disoder|REM sleep behavior disorder]], sleep reversal)
*[[Ataxia]]