View source for Sporadic necrotizing encephalitis

=== Clinic ===

* The clinical syndrome is often characterized by the rapid onset of fever, headache, seizures, focal neurologic signs, and impaired consciousness. <ref>Hanley DF, Johnson RT, Whitley RJ. Yes, brain biopsy should be a prerequisite for herpes simplex encephalitis treatment. Arch Neurol 1987; 44:1289.</ref>

* ANE or sometimes necrotizing encephalitis or infection-induced acute encephalopathy (IIAE) is a rare type of encephalopathy that occurs following a viral infection. 
** [[INFL, Influenza virus|Influenza A and B]]
** [[HHV-6, Human Herpes Virus 6|HHV-6]]
** [[HSV-1, Herpes Simplex Virus|HSV-1]] is the most common cause of sporadic necrotizing [[encephalitis]]
* Multiple subtypes, associated with specific genes have been found.


=== Symptoms ===

* Typical symptoms of an infection, such as fever, cough, congestion, vomiting, and diarrhea, for a few days. 
* Following flu-like symptoms, neurological problems such as 
** [[Seizure]]
** [[Hallucination]]
** [[Ataxia]]
** Abnormal muscle tone
** Coma