Enteropathy

Clinic

• It refers to any pathology of the intestine that prevents the body from absorbing nutrition
• Enteritis specifically refers to an inflammation of the intestine, and is thus a more specific term than "enteropathy", the two phrases are sometimes used interchangeably.
• If the condition also involves the stomach, it is known as "gastroenteropathy".

Types

• Enteropathy-associated T-cell lymphoma
• Environmental enteropathy (Tropical enteropathy): An incompletely defined syndrome of inflammation related to the quality of the environment. Signs and symptoms include reduced absorptive capacity and reduced intestinal barrier function of the small intestine. It is widespread among children and adults in low- and middle-income countries.
• Eosinophilic enteropathy: A condition in which eosinophils accumulate in the GI tract and in the blood. Eosinophil build up in the GI tract can result in polyp formation, tissue break down, inflammation, and ulcers.
• Coeliac disease: (Gluten-Sensitive Enteropathy)

• HIV enteropathy: Characterized by chronic diarrhea more than one month in duration with no obvious infectious cause in an HIV-positive individual. Thought to be due to direct or indirect effects of HIV on the enteric mucosa.
• Immunodysregulation polyendocrinopathy and enteropathy, X-linked
• Protein losing enteropathy. It is related to CMV and MTB
• Radiation enteropathy

Autoimmune enteropathy

• It is an extremely rare condition characterized by an abnormal intestinal immune response
• Typically manifests within the first 6 months of life as severe, intractable diarrhea that does not respond to dietary modification.
• Affected individuals frequently present with other signs of autoimmunity. The diagnosis is made based on a characteristic combination of clinical symptoms, laboratory studies, and histological features on small bowel biopsy.
• It is associated with Autoimmune polyglandular syndrome type 1 (APS-1)