Interstitial nephritis: Difference between revisions

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=== Clinic ===
=== Clinic ===


* Also known as tubulointerstitial [[nephritis]], is inflammation of the area of the kidney known as the renal interstitium, which consists of a collection of cells, extracellular matrix, and fluid surrounding the renal tubules.  
* Also known as tubulointerstitial [[nephritis]]  
* Renal interstitium participate in the fluid and electrolyte exchange as well as endocrine functions of kidney.
* It is inflammation of renal interstitium, which consists of a collection of cells, extracellular matrix, and fluid surrounding the renal tubules.
* Common causes include infection, or reaction to medication such as an analgesic, anti-inflammatory, or antibiotics  
* Renal interstitium participate in the fluid and electrolyte exchange as well as endocrine functions.
 
 
=== Signs / Symptoms ===
 
* Fever is the most common, occurring in 30-50% of patients, particularly those with drug-induced interstitial nephritis.  
* Nausea, vomiting, fatigue, lack of appetite, and weight loss.
* Flank pain, Pain with urination
* Hematuria
* [[Hypertension]]
* Classic triad of symptoms: Rash + Arthralgia + Eosinophilila (5-10% of patients)
 
 
=== Causes ===
* Dynamic: Infection
* Static: Reaction to drugs such as an analgesic, anti-inflammatory, or antibiotics
 


=== Miasm ===
=== Miasm ===
[[HFRS, Hemorrhagic Fever with Renal Syndrome|HFRS]]
[[HFRS, Hemorrhagic Fever with Renal Syndrome|HFRS]]

Latest revision as of 00:46, 27 April 2023

Clinic

  • Also known as tubulointerstitial nephritis
  • It is inflammation of renal interstitium, which consists of a collection of cells, extracellular matrix, and fluid surrounding the renal tubules.
  • Renal interstitium participate in the fluid and electrolyte exchange as well as endocrine functions.


Signs / Symptoms

  • Fever is the most common, occurring in 30-50% of patients, particularly those with drug-induced interstitial nephritis.
  • Nausea, vomiting, fatigue, lack of appetite, and weight loss.
  • Flank pain, Pain with urination
  • Hematuria
  • Hypertension
  • Classic triad of symptoms: Rash + Arthralgia + Eosinophilila (5-10% of patients)


Causes

  • Dynamic: Infection
  • Static: Reaction to drugs such as an analgesic, anti-inflammatory, or antibiotics


Miasm

HFRS

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