Autoimmune Polyendocrine Syndrome: Difference between revisions

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There are two distinct types APS-1 and APS-2
There are two distinct types APS-1 and APS-2


== APS-1 ==
== APS-2 ==


===Clinic===
===Clinic===

Revision as of 22:21, 5 April 2023

There are two distinct types APS-1 and APS-2

APS-1

APS-2

Clinic

  • APS-2 a form of autoimmune polyendocrine syndrome also known as PAS II
  • It is the most common form of the polyglandular failure syndromes.
  • PAS II is defined as the association between autoimmune Addison's disease and either autoimmune thyroid disease, type 1 diabetes, or both.
  • It is heterogeneous and has not been linked to one gene.
  • APS-II affects women to a greater degree than men.

Signs and symptoms

  • Hashimoto thyroiditis: Nausea, Frequent urination, Palpitations, Weight loss, Anorexia
  • Low blood pressure
  • Hypoparathyroidism
  • Myalgia
  • Graves' disease
  • Anaemia
  • Hypogonadism
  • Diabetes mellitus

Entities / Miasms

EBV MTB MMP B19 CXB HCV HSV RBL
Hashimoto thyroiditis ++ +++ + + +++ + +
Adrenal insufficiency ++
Diabetes Insulin dependent +++ +++ +++ +++
Female, Infertility / Oophoritis +++ +++
Anemia +++ +++ +++ +++ +++