LGI1 encephalitis

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Clinic

  • Leucine-rich glioma-inactivated-1 antibody encephalitis is an autoimmune encephalitis
  • Patients may present with subacute onset of memory loss, behavioral disturbances and seizures.
  • Peripheral manifestations, such as neuropathy or autonomic dysfunction, often coexist but may also occur without central involvement.
  • Faciobrachial dystonic seizure (FBDS)
  • Paroxysmal dizziness spells without alteration of consciousness


2 Entities

  • Memory loss
  • Behavior change
  • Seizure
  • Dystonia (Rigidity + ChoreAthetosis)
  • Hypertention

3 Miasms

JE