Myopathy

Clinic

• It is a disease of the muscle in which the muscle fibers do not function properly, therefore results in muscular weakness
• Muscle Cramps / Stiffness / Spasm / Tetany can also be associated with myopathy.
• Muscular disease can be classified as neuromuscular or musculoskeletal in nature.
• Some conditions, such as myositis, can be considered both neuromuscular and musculoskeletal.

Types

Inherited forms

• Myotonia: Neuromyotonia

Acquired

• Inflammatory / Autoimmune myopathies
• Dermatomyositis
• Polymyositis
• Myositis ossificans
• Rhabdomyolysis and Myoglobinuria

• Statin-associated autoimmune myopathy

Myocardium / cardio-myopathy

• Acute myocarditis
• Cardiomyopathy
• Endomyocardial (eosinophilic) disease
• Eosinophilic myocarditis
• Endomyocardial (tropical) fibrosis
• Löffler's endocarditis
• Endocardial fibroelastosis
• Endocrine and metabolic disorders – hypokalemia, hypocalcemia, hypercalcemia

Onset in adulthood

• Inflammatory myopathies – polymyositis, dermatomyositis, inclusion body myositis, viral (HIV)
• Infectious myopathies

Entities

• Myopathy : CMV
• Myositis: DHF, INFL, RTV, VZV
• General Myositis: CXA, CXB, ECHO
• Dermatomyositis: CXA, CXB, ECHO, WNE