Nerocognitive considerations

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Revision as of 11:45, 12 March 2023 by Oldver>Mehrdad (→‎Functional oriented study)
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There is no doubt that Nerocognitive area is the most complex area of diseases in the body. Apart from the incomplete information of neuroscience, the network function of neurons should be considered as the solution of evolution to provide the most economical organ of the body. This means that a neuron, by creating a network of 10,000 neurons around itself, sometimes participates in several complex brain functions at the same time, and this challenges the simple mind of Newtonian scientists.


Since the goal of TLT theory is to provide a solution to simplify the understanding of disease patterns, and this goal was met with significant success in pilot studies on other body organs except the brain, I was encouraged to implement this model on the brain as well. Which, of course, was a wonderful dream that is gradually turning into a deadly nightmare. Until I realized that there are special rules in the brain that make it dependent on other organs. It is better to say that it may not be possible to claim with certainty that such laws are inherent in the brain, but these laws can be included in brain modeling to simplify and understand the controversy in the brain.


The first thing that comes to the mind of every viewer is the multiple dimensions of brain activity.

Movement - Sense - Cognition - Emotion - perception

This area is well known in neuroscience and I will use it as much as possible, of course, on the condition that I organize my toolbox first.

The next area is the quantification of brain function. The key question in any brain disorder is whether this disorder causes a decrease or an increase in brain function. Obviously, this ruler can be used in all the areas mentioned above

Thus, with these two tools, I will be able to classify all brain diseases in a simple way. For example, depression slows down everything, especially in the field of emotion, perception, cognitive functions, etc., and the difference with catatonia is that catatonia obviously slows down the motor system and Depression leads the emotional system and hypomania leads the patient to the rhythmic increase and decrease of the emotional system

Functional oriented study

There are different ways to classify the disease. Classification based on etiology, structural disorder, histologic deviation or pathology and functional classification. The ultimate goal is that these categories eventually reach the same conclusion. For example, in pharyngitis, pharyngeal tissue is inflamed and inflammatory cells can be seen in sampling. The structure of the tissue changes macroscopically and becomes covered with exudative secretion. Its function in swallowing and breathing is also disturbed, and this becomes a clean disease called pharyngitis

This happens in most diseases except brain diseases. Brain has another story. Of course, the ideal is what was said, but this goal still seems unattainable. Moreover, the etiology of most brain diseases is still unclear. The symptoms of brain diseases overlap a lot, and the course of symptoms is so variable that it is difficult to imagine a clear rule for them. One way is to tell patients to wait until the exact cause of their illness is determined. But since no one has the patience of Job, it is necessary to start the treatment of brain diseases with this little wealth.

Today, most brain diseases are diagnosed in the clinical field rather than depending on para clinical diagnosis. Neuropsychologists are not waiting for para clinical documentation to start treatment

This means that brain function takes precedence over its structure. If we add the Compensation ability of brain parts which is now known as neuroplacticity, we simply give the right to this view.

The second point is the emphasis of TLT theory on the dynamics of diseases. In fact, according to the definition of miasm, the repeating pattern is the function of the disease. Although the role of histological destruction in occurrence of diseases is not deniable, what is observed by the miasm and considered as the goal of treatment is not the change of the tissue structure, but the improvement of its function.

These are two good reasons why I prefer a functional approach to categorizing brain diseases.

Cranial nerves
Central Peripheral
Cranial nerves palsy


Hearing impaired


Facial palsy

Trigeminal neuralgia

Diplopia (3, 4, 6)

Bels palsy

Cortical Blindness Peripheral Blindness
Central labyrintitis (Hearing + Ataxia) only ataxia
Anosemia Coryza, Rhinitis
/
Decreased Increased Changeable
Cognition impaired
Perception Impaired Hallucination
Thought Dementia Delusion
Memory / Concentration Impaired Anxiety / Obsession
Mood Depression Agitation / Anger/ Fear Changeable
Sensory
Peripheral Central
Decreased Hypostasia
Increased Hyper stasia Central sensitization
Deviared Dysesthesia

Pruritis

Movement
LMN UMN Central
Decreased LMN Brady kinesia
Increased Myoclonous

Clonous

Jerking / Twitching


Hyper kinetics
Hyper kinetics
Rhythmic Non-Rhythmic
Simple Tremor
Complex Chorea / Sterotypia / Preservation / Tic/
Peripheral
Central Rigidity
Peripheral motor neuron disease
Reflexes Tonocity Hyper kinetics Muscular bulk
UMN Hyper reflexia Spasticity

Hypertonia

Clonus ---
LMN Hypo reflexia Hypotonia Fasciculations Atrophy
Reflexes
Hyper
Central
Peripheral LMN
UMN