Anti CASPR2 encephalitis

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Revision as of 22:37, 19 March 2023 by Oldver>Mehrdad (Created page with "=== Clinic === The most frequent syndromes included * Limbic encephalitis (42%) * Morvan syndrome (29%) === Sign / Symptoms === 77% of the patients had ≥3 of the following symptoms: * Encephalopathy (Cognitive deficits / Seizures) * Cerebellar dysfunction * Peripheral nervous system hyperexcitability * Dysautonomia * Insomnia * Neuropathic pain * Weight loss * Thy...")
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Clinic

The most frequent syndromes included

Sign / Symptoms

77% of the patients had ≥3 of the following symptoms:

  • Encephalopathy (Cognitive deficits / Seizures)
  • Cerebellar dysfunction
  • Peripheral nervous system hyperexcitability
  • Dysautonomia
  • Insomnia
  • Neuropathic pain
  • Weight loss
  • Thymoma, occurred in 19% of the patients [1]
  1. ↑ van Sonderen A, Ariño H, Petit-Pedrol M, Leypoldt F, Körtvélyessy P, Wandinger KP, Lancaster E, Wirtz PW, Schreurs MW, Sillevis Smitt PA, Graus F, Dalmau J, Titulaer MJ. The clinical spectrum of Caspr2 antibody-associated disease. Neurology. 2016 Aug 2;87(5):521-8. doi: 10.1212/WNL.0000000000002917. Epub 2016 Jul 1. PMID: 27371488; PMCID: PMC4970662.
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