Diabetes insipidus
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Clinic
- Diabetes insipidus (DI) is a condition characterized by large amounts of dilute urine and increased thirst.
- The amount of urine produced can be nearly 20 liters per day. Reduction of fluid has little effect on the concentration of the urine. Complications may include dehydration or seizures.
- There are four types of DI, each with a different set of causes.
- Central DI is due to a lack of Antidiuretic hormone production. This can be due to injury to the hypothalamus or pituitary gland or genetics.
- Nephrogenic DI occurs when the kidneys do not respond properly to vasopressin.
- Dipsogenic DI is a result of excessive fluid intake due to damage to the hypothalamic thirst mechanism. It occurs more often in those with certain psychiatric disorders or on certain medications.
- Gestational DI occurs only during pregnancy. Diagnosis is often based on urine tests, blood tests and the fluid deprivation test. Diabetes insipidus is unrelated to diabetes mellitus and the conditions have a distinct mechanism, though both can result in the production of large amounts of urine.
Signs / Symptoms
- Excessive urination
- Extreme thirst
- Increased fluid intake esp for cold water
Tissue Salt Remedies
- NM: Polyuria, Profuse pale urination