NVCJD, New Variant Creutzfeldt Jakob Disease

Core

NVCJD focuses on Pulvinar nucleus of Thalamus

• Visual attention / Impaired concentration
• Visual salience
• Social cognition
• Neglect syndrome / Disorientation = Spatial Confusion
• Gait disorder /Incoordination

Entities

Upper motor neuron

• Central inhibitory control (Pyramidal) has been removed from the spinal cord
• Hypertonia (Possibly equals to Spasticity)
• Myoclonus
• Hyperreflexia
• Primitive reflexes

Psychosis

• Auditory / Visual Hallucination
• Delusions
• Behavioral change
• Agitation, Irritability, Anger, Sleeplessness

• Dysesthesia , Painful Paresthesia

Ataxia (Maybe)

• Incoordination
• Gait abnormalities

Autonomic dysfunction (Maybe)

• Recent researches suggest that vCJD attack brain from the GI tract autonomic nervous system (Both parasympathetic and sympathetic)
• Dysarthria (Possibly UMN Dysarthria)
• Dysphagia
• Urine Incontinence

Choreoathetosis

Diseases

Dementia

• Disorientation
• Impaired Cognition
• Memory; weakness
• Depression
• Anxiety

Schizophrenia

• Psychosis
• Hallucination, Auditory, Visual
• Delusion
• Altered though pattern
• Behavioral change
  

Remedies

2. LACH, BELL
3. Stram
4. Crot-c, Carbn-s