Ankylosing Spondylitis: Difference between revisions

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=== Clinic ===
=== Clinic ===


* AS is a type of arthritis characterized by long-term inflammation of the joints of the spine typically where the spine joins the pelvis.
* AS is a type of [[arthritis]] characterized by long-term inflammation of Spine and Pelvic joints  
* AS is a systemic rheumatic disease, meaning it affects the entire body.  
* AS is a systemic rheumatic disease, meaning it affects the entire body.  
* Occasionally areas affected may include other joints such as the shoulders or hips, eye and bowel problems may occur as well as back pain.  
* Occasionally areas affected may include other joints such as the shoulders or hips, eye and bowel problems may occur as well as back pain.  
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* Signs and symptoms often appear gradually, with peak onset between 20 -30 years of age.
* Signs and symptoms often appear gradually, with peak onset between 20 -30 years of age.
* Initial symptoms are usually a chronic dull pain in the lower back or gluteal region combined with stiffness of the lower back.
* Initial symptoms are
* Pain and stiffness awakens them in the early morning hours.
** Chronic dull Pain / Stiffness  in the lower back or gluteal region, agg in morning
* As the disease progresses, loss of spinal mobility and chest expansion, with a limitation of anterior flexion, lateral flexion, and extension of the lumbar spine are seen.
** Progressive loss of spinal mobility and chest expansion
* Systemic features are common with weight loss, fever, or fatigue often present.
** Weight loss, fever, or fatigue
* Pain is often severe at rest but may improve with physical activity.  
** Pain is often severe at rest and improve with physical activity.
* Inflammation and pain may recur to varying degrees regardless of rest and movement.
** Hips / Shoulders / Knees / Ankles / Feet / Heel Arthritis  
* AS can occur in any part of the spine or the entire spine, often with pain localized to either buttock or the back of the thigh from the sacroiliac joint.
** Less commonly ectasia of sacral nerve root sheaths.
* Arthritis in the hips and shoulders may also occur.
* When the condition presents before the age of 18, AS is more likely to cause pain and swelling of large lower limb joints, such as the knees.
* In prepubescent cases, pain and swelling may also manifest in the ankles and feet where heel pain and enthesopathy commonly develop. Less common occurrences include ectasia of the sacral nerve root sheaths.




=== Extra Sign/ Symptoms ===
=== Extra Sign/ Symptoms ===


* About 30% of people with AS will also experience anterior [[Uveitis remedies|uveitis]] causing eye pain, redness, and blurred vision.
* Anterior [[uveitis]] causing eye pain, redness, and blurred vision. (About 30%)
* Cardiovascular involvement may include inflammation of the aorta, aortic valve insufficiency or disturbances of the heart's electrical conduction system.
* Aortic valve inflammation  
* [[Lung fibrosis]]  
* [[Lung fibrosis]]  


=== Miasms ===
=== [[Viral miasms|Miasms]] ===
[[MTB, Mycobacterium tuberculosis|MTB]]
 
* [[MTB, Mycobacterium tuberculosis|MTB]]

Revision as of 23:31, 23 November 2023


Clinic

  • AS is a type of arthritis characterized by long-term inflammation of Spine and Pelvic joints
  • AS is a systemic rheumatic disease, meaning it affects the entire body.
  • Occasionally areas affected may include other joints such as the shoulders or hips, eye and bowel problems may occur as well as back pain.
  • Joint mobility in the affected areas generally worsens over time.
  • Causation is unknown
  • There is no known cure for it


Signs and symptoms

  • Signs and symptoms often appear gradually, with peak onset between 20 -30 years of age.
  • Initial symptoms are
    • Chronic dull Pain / Stiffness in the lower back or gluteal region, agg in morning
    • Progressive loss of spinal mobility and chest expansion
    • Weight loss, fever, or fatigue
    • Pain is often severe at rest and improve with physical activity.
    • Hips / Shoulders / Knees / Ankles / Feet / Heel Arthritis
    • Less commonly ectasia of sacral nerve root sheaths.


Extra Sign/ Symptoms

  • Anterior uveitis causing eye pain, redness, and blurred vision. (About 30%)
  • Aortic valve inflammation
  • Lung fibrosis

Miasms

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