Progressive bulbar palsy: Difference between revisions

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=== Clinic ===
=== Clinic ===


* PBP belongs to a group of disorders known as [[motor neuron diseases]].  
* PBP belongs to [[Motor Neuron Disease|motor neuron diseases]]. It is located under the umbrella of Bulbar palsy since it attacks the nerves supplying of bulbar muscles.  
* PBP is a disease that attacks the nerves supplying the bulbar muscles.  
* It is characterized by the degeneration of motor neurons in the cerebral cortex, spinal cord, brain stem and pyramidal tracts.
* These disorders are characterized by the degeneration of motor neurons in the cerebral cortex, spinal cord, brain stem, and pyramidal tracts.  
* This specifically involves the [[Glossopharyngeal nerve]] (IX), [[Vagus nerve]] (X), and [[Hypoglossal nerve]] (XII).
* This specifically involves the glossopharyngeal nerve (IX), vagus nerve (X), and hypoglossal nerve (XII).
* It should not be confused with [[pseudobulbar palsy]] or progressive spinal muscular atrophy.  
* ICD-11 lists progressive bulbar palsy as a variant of [[ALS, Amyotrophic Lateral Sclerosis remedies|ALS]]
* ICD-11 lists progressive bulbar palsy as a variant of [[ALS, Amyotrophic Lateral Sclerosis remedies|ALS]]


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=== Signs / Symptoms ===
=== Signs / Symptoms ===


* [[Glossopharyngeal nerve]]
* [[Glossopharyngeal nerve]]: Reduced gag reflexes
**Reduced gag reflexes  
* [[Vagus nerve]]: Weak palatal movements
* [[Vagus nerve]]
**Weak palatal movements  
*[[Hypoglossal nerve]]:  
*[[Hypoglossal nerve]]:  
**Fasciculations
**[[Fasciculation|Fasciculations]]
**Progressive difficulty with talking and swallowing
**Progressive difficulty with talking and swallowing
**Weak movement of the facial muscles and tongue
**Weak movement of the facial muscles and tongue
**Difficulty with pronunciations, particularly lateral consonants (linguals) and velars  
**Difficulty with pronunciations, particularly lateral consonants (linguals) and velars  
**Problems with drooling saliva  
**Problems with drooling saliva  
* If [[corticobulbar tract]] is affected a pseudobulbar affect with emotional changes may occur
* If [[corticobulbar tract]] is affected a [[Pseudobulbar affect]] may occur




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* [[Pseudobulbar palsy]]
* [[Pseudobulbar palsy]]
* [[Progressive muscular atrophy|Progressive spinal muscular atrophy]]
* 25% of patients eventually develop ALS
=== Miasms / ===
* Paralysis, Bulbar
* Mouth, Speech , Difficult
* Dysphagia
* Mouth, Paralysis, Soft palate


*Gagging and choking increases the risk of pneumonia
=== Entities ===
* 25% of patients eventually develop ALS
[[PLV, Polio Virus|PLV]]

Latest revision as of 22:22, 13 April 2023

Clinic

  • PBP belongs to motor neuron diseases. It is located under the umbrella of Bulbar palsy since it attacks the nerves supplying of bulbar muscles.
  • It is characterized by the degeneration of motor neurons in the cerebral cortex, spinal cord, brain stem and pyramidal tracts.
  • This specifically involves the Glossopharyngeal nerve (IX), Vagus nerve (X), and Hypoglossal nerve (XII).
  • ICD-11 lists progressive bulbar palsy as a variant of ALS


Signs / Symptoms


Related disease

Miasms /

  • Paralysis, Bulbar
  • Mouth, Speech , Difficult
  • Dysphagia
  • Mouth, Paralysis, Soft palate

Entities

PLV

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