Fasciculation

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Clinic

  • Also known as muscle twitch
  • It is a Sign, characterized by spontaneous, involuntary muscle contraction and relaxation, involving fine muscle fibers.
  • Fasciculation is a part of LMN, as an entity.
  • Fasciculations arise as a result of spontaneous depolarization of a lower motor neuron leading to the synchronous contraction of all the skeletal muscle fibers within a single motor unit.


Causes

  • Up to 70% of all healthy people, though for most, it is quite infrequent.
  • Fasciculations can be caused by anxiety, caffeine or alcohol and thyroid disease and some drugs
  • Magnesium deficiency is a common cause


Related disease

  • Tics must also be distinguished from fasciculations. Small twitches of the upper or lower eyelid, for example, are not tics, because they do not involve a whole muscle, rather are twitches of a few muscle fibre bundles, that are not suppressible.
  • Myokymia: Fasciculation is intermittent bursts of contraction and is seen as a single muscle twitch at a time. It can change location within the muscle or can recur in the same area at some intervals, but not rhythmic. Myokymia is somewhat few rhythmic and slower contractions in muscles at the same place.


Related entities

Miasms