Gastroparesis: Difference between revisions
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===Mechanism=== | ===Mechanism === | ||
*On the molecular level, it is thought that gastroparesis can be caused by the loss of neuronal nitric oxide expression | *On the molecular level, it is thought that gastroparesis can be caused by the loss of neuronal nitric oxide expression | ||
*Other important components of the stomach are the interstitial cells of Cajal (ICC) which act as a pacemaker since they transduce signals from motor neurons to produce an electrical rhythm | *Other important components of the stomach are the interstitial cells of Cajal (ICC) which act as a pacemaker since they transduce signals from motor neurons to produce an electrical rhythm | ||
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|'''Abdominal Bloating''' | |'''Abdominal Bloating''' | ||
|Lyc | | | ||
| | === [[Lyc , Lycopodium clavatum|Lyc]] === | ||
| | |||
* The bloating is noted even after eating a little bit of food. | |||
* Constrictive pains in the stomach that are relieved by rubbing the stomach. (Maybe) | |||
* There may be a gnawing and gripping sensation in the stomach, and clothes around the stomach may cause uneasiness. | |||
* Loss of appetite | |||
* Coldness in the stomach | |||
* Violent hiccoughs. | |||
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=== [[Hydr, Hydrastis Canadensis|Hydr]] === | === [[Hydr, Hydrastis Canadensis|Hydr]] === | ||
|'' | | | ||
* ''S''ensation of a lump in the stomach followed by regurgitation that causes vomiting of the food eaten | |||
* Distressing and cutting pain in the stomach (Maybe) | |||
* Weakness and weight loss. | |||
| | | | ||
|- | |- | ||
|'''Stomach Pain after Eating''' | |'''<big>Stomach Pain after Eating</big>''' | ||
|Puls | | | ||
|'' | === [[Puls, Pulsatilla pratensis|Puls]] === | ||
| | |||
* ''P''ain usually begins an hour after eating. | |||
* Chilly | |||
* Tightness in the stomach (Maybe) | |||
* Stomach is sensitive to the least pressure. | |||
* Belching that tastes like food may be present | |||
* Symptoms tend to get work after eating fatty food and fruits. | |||
* Dry mouth, bitter taste in the mouth and a lack of thirst. | |||
| | | | ||
|- | |- | ||
|''' | |'''<big>Weight in Stomach</big>''' | ||
|Chin | | | ||
| | === [[Chin, China Officinalis|Chin]] === | ||
| | |||
* Weak and slow digestion | |||
* Belching of bitter taste is present | |||
* Food may be regurgitated | |||
* Rumbling and pulsating sensation at pit of stomach. | |||
| | | | ||
|- | |- | ||
|''' | |'''<big>Hard Knot in Stomach</big>''' | ||
|Nux-v | | | ||
|'' | === [[Nux-v , Nux Vomica|Nux-v]] === | ||
| | |||
* ''S''tomach area is sensitive to touch | |||
* Nausea or vomiting, and retching. (Maybe) | |||
* The vomit contains undigested food or greenish matter. | |||
* Vomiting relieves nausea. | |||
* Sour taste in the mouth. ([[Chin ₳ Nux-v]]) | |||
| | | | ||
|- | |- | ||
|'''Fetid Belchings''' | |'''Fetid Belchings''' | ||
|Bism | | | ||
|'' | === [[Bism, Bismuthum subnitricum|Bism]] === | ||
| | |||
* ''F''ood lies in the stomach for several days due to weak digestion. | |||
* Pressure / Sensation of a load in the stomach after eating, which is followed by vomiting | |||
* Stomach pain amel by bending backward | |||
| | | | ||
|- | |- | ||
|'''Heartburn/Acid Reflux''' | |'''<big>Heartburn/ Acid Reflux</big>''' | ||
|Carb-v | | | ||
| | === [[Carb-v, Carbo vegetabilis|Carb-v]] === | ||
| | |||
* Sour belchings / Water brash after eating + Fullness and a tensed sensation in stomach. | |||
* Epigastric region is sensitive and tender to touch. | |||
* Contractive pain in stomach extending to the chest | |||
* Even eating the simplest kind of food agg him | |||
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|} | |} |
Latest revision as of 05:26, 23 January 2024
Clinic
- Also called delayed gastric emptying, is an entity belonged to category of GI motility disorders
- Weak peristalsis of stomach, resulting in prolonged food and liquid remaining in stomach
- This can result in irregular absorption of nutrients, inadequate nutrition, and poor glycemic control.
- Probable mechanism is autonomic neuropathy (Vagus nerve)
- Uncontrolled diabetes mellitus is its major causation.
- Other causes include post-infectious and trauma to the vagus nerve.
- Idiopathic gastroparesis (33% of all chronic cases); Due to an autoimmune response triggered by an acute viral infection:
- Gastroenteritis
- Mononucleosis
Signs / Symptoms
- Symptoms include Nausea (Esp Morning), Vomiting, Abdominal pain, Early satiety, Abdominal bloating and Heartburn.
- Other symptoms:
- Myalgia
- Erratic blood glucose levels
- Lack of appetite
- Muscle weakness
- Night sweats
- Palpitations
- Spasms of the stomach wall
- Constipation or infrequent bowel movements
- Weight loss, malnutrition
- Dysphagia
Miasms
Fantastically, many accompanied Sign / Symptoms of Gasteroparesis are similar to PLV such as muscular weakness, Dyspahgia
Related entities
Related Disease
- Connective tissue diseases such as scleroderma
- Ehlers–Danlos syndrome
- Parkinson's disease
- Multiple system atrophy. It may occur as part of a mitochondrial disease.
- Opioids and anticholinergic medications can cause medication-induced gastroparesis.
- Damage to the vagus nerve, such as abdominal surgery
- Heavy cigarette smoking
Mechanism
- On the molecular level, it is thought that gastroparesis can be caused by the loss of neuronal nitric oxide expression
- Other important components of the stomach are the interstitial cells of Cajal (ICC) which act as a pacemaker since they transduce signals from motor neurons to produce an electrical rhythm
Pathogenesis of symptoms in diabetic gastroparesis include:
- Loss of gastric neurons containing nitric oxide synthase (NOS) is responsible for defective accommodation reflex, which leads to early satiety and postprandial fullness.
- Impaired electromechanical activity in the myenteric plexus is responsible for delayed gastric emptying, resulting in nausea and vomiting.
- Sensory neuropathy in the gastric wall may be responsible for epigastric pain.
- Abnormal pacemaker activity (tachybradyarrhythmia) may generate a noxious signal transmitted to the CNS to evoke nausea and vomiting.
Gastroparesis black box
Entities | Miasms | Remedies |
---|---|---|
Gastric Dilation | PLV |
|
Remedies
Abdominal Bloating |
Lyc |
|
|
Vomiting of Food |
Hydr |
|
|
Stomach Pain after Eating |
Puls |
|
|
Weight in Stomach |
Chin |
|
|
Hard Knot in Stomach |
Nux-v |
|
|
Fetid Belchings |
Bism |
|
|
Heartburn/ Acid Reflux |
Carb-v |
|