RBD, Rapid Eye Movement Sleep Behavior Disoder: Difference between revisions

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=== Main symptoms ===
=== Main symptoms ===
*RBD is characterized by the dreamer acting out their dreams, with complex behaviors.
*RBD is characterized by the dreamer acting out their dreams, with complex behaviors.
* Dreams often involve Violent / Aggressive actions, Screaming, Shouting, Laughing, Crying, Arm flailing, Kicking, Punching, Choking, and Jumping
* Dreams often involve Violent / Aggressive actions such as Screaming, Shouting, Laughing, Crying, Arm flailing, Kicking, Punching, Choking, and Jumping
* The sleeping person may be unaware of these movements.
* The sleeping person may be unaware of these movements.


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* [[Autonomic Nervous System|Autonomic dysfunction]] (Orthostatic hypotension, Constipation, Urinary problems and Sexual dysfunction)
* [[Autonomic Nervous System|Autonomic dysfunction]] (Orthostatic hypotension, Constipation, Urinary problems and Sexual dysfunction)
* Depression
* Depression
{| class="wikitable"
|+
!
!TBE
!HSV-1
!JE
!HSV-2
|-
|Seizure
| +++
| +++
| +++
| +++
|-
|Hallucination
| +++
| +++
| +++
| +++
|-
|Delusion
| +++
| +++
| +++
| +++
|-
|Delirium
| +++
| +++
| +++
| +++
|-
|Orthostatic hypotension
| +++
| +++
|
|
|-
|Constipation
|
| +++
|
| +++
|-
|Urinary in continence
| +++
|
|
|
|-
|Dilated pupils
|
|
| +++
|
|-
|Anosmia
|
| +++
|
| +++
|-
|[[Cerebral achromatopsia]]
|
|
|
|
|}


=== Related disease ===
=== Related disease ===
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* [[Obstructive sleep apnea|Severe obstructive sleep apnea]]
* [[Obstructive sleep apnea|Severe obstructive sleep apnea]]
* [[Dissociative disorders]]
* [[Dissociative disorders]]


=== Entities / Miasms ===
=== Entities / Miasms ===


* I seems that [[Extrapyramidal|extrapyramidal tracts]] are involved actively in RBD, therefore it belongs to [[Extrapyramidal|EPS]] [[Cluster of disease|COD]] whose main miasms are [[JE, Japanese encephalitis|JE]], [[WNE, West Nile Encephalitis|WNE]], [[GSS, Gerstmann Straussler Scheinker syndrome|GSS]], [[CJD, Creutzfeldt Jakob Disease|CJD]] and [[FFI, Fatal Familial Insomnia|FFI]]
* I seems that [[Extrapyramidal|extrapyramidal tracts]] are involved actively in RBD, therefore it belongs to [[Extrapyramidal|EPS]] [[Cluster Of Entities|COE]] whose main miasms are [[JE, Japanese encephalitis|JE]], [[WNE, West Nile Encephalitis|WNE]], [[GSS, Gerstmann Straussler Scheinker syndrome|GSS]], [[CJD, Creutzfeldt Jakob Disease|CJD]] and [[FFI, Fatal Familial Insomnia|FFI]]
* Color vision impairment (Cerebral achromatopsia) and Anosmia are useful guides which lead us to [[CJD, Creutzfeldt Jakob Disease|CJD]]
* Color vision impairment ([[Cerebral achromatopsia]]) and Anosmia are useful guides which lead us to [[CJD, Creutzfeldt Jakob Disease|CJD]]

Latest revision as of 00:41, 16 May 2023

Clinic

  • RBD is a parasomnia, A sleep disorder in which people act out their dreams. It involves abnormal behavior during REM sleep.
  • The major feature of RBD is loss of muscle atonia during otherwise intact REM sleep.
  • Loss of motor inhibition leads to sleep behaviors ranging from simple limb twitches to more complex integrated movements
  • RBD is a very strong predictor of progression to Parkinson's disease or dementia with Lewy bodies


Main symptoms

  • RBD is characterized by the dreamer acting out their dreams, with complex behaviors.
  • Dreams often involve Violent / Aggressive actions such as Screaming, Shouting, Laughing, Crying, Arm flailing, Kicking, Punching, Choking, and Jumping
  • The sleeping person may be unaware of these movements.


Other symptoms

TBE HSV-1 JE HSV-2
Seizure +++ +++ +++ +++
Hallucination +++ +++ +++ +++
Delusion +++ +++ +++ +++
Delirium +++ +++ +++ +++
Orthostatic hypotension +++ +++
Constipation +++ +++
Urinary in continence +++
Dilated pupils +++
Anosmia +++ +++
Cerebral achromatopsia

Related disease


Causes

  • Loss of normal voluntary muscle atonia during REM sleep results in motor behavior in response to dream content
  • Brainstem circuits (Pontomedullary brainstem) that control atonia during REM sleep may be damaged.
  • REM sleep circuits are located in caudal brainstem structures are the same structures that are implicated in the synucleinopathies.
    • Motor deficits like those seen in RBD are known to result from lesions in those circuits.


Differential Diagnosis


Entities / Miasms

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