Schizophrenia

Clinic

• It is a mental disorder characterized by continuous or relapsing episodes of psychosis.
• Major symptoms include Hallucinations (typically hearing voices), Delusions, and Disorganized thinking.
• Other symptoms include Social withdrawal, Decreased emotional expression, and Apathy.
• Symptoms typically develop gradually, begin during young adulthood, and in many cases never become resolved.
• Most of them have other mental disorders, esp Substance use disorders, Depressive disorders, Anxiety disorders, and OCD.

Positive symptoms

• Delusions, hallucinations, and disorganized thoughts and speech, typically regarded as manifestations of psychosis.
• Hallucination (80% of Cases) most commonly involve hearing (Often hearing voices) but other senses maybe involved.
• Hallucination are also typically related to the content of the delusional theme.
• Delusions are bizarre or persecutory in nature.
• Thought disorders can include Thought blocking, and Disorganized speech.

Negative symptoms

• Blunted affect – showing flat expressions or little emotion
• Alogia: Poverty of speech
• Anhedoni: Inability to feel pleasure
• Asociality: Lack of desire to form relationships
• Avolition: Lack of motivation and apathy.
• Avolition and anhedonia are seen as motivational deficits resulting from impaired reward processing.
• Apathy includes avolition, anhedonia and social withdrawal; diminished expression includes blunt affect, and alogia.
• Apathy (50%) is related to disrupted cognitive processing affecting memory and planning including goal-directed behavior.

Cognitive symptoms

• Cognitive symptoms (70%) are most pronounced in early onset and late-onset illness. These are often evident long before the onset of illness in the prodromal stage.
• Cognitive deficits are core features and may be of Neurocognition (nonsocial) or of Social cognition.
  • Neurocognition is the ability to receive and remember information, and includes verbal fluency, memory, reasoning, problem solving, speed of processing, and auditory and visual perception.
  • Mostly Verbal memory and attention are affected. Verbal memory impairment is associated with a decreased level of semantic processing (relating meaning to words).
  • Episodic memory. An impairment in visual perception that is consistently found in schizophrenia is that of visual backward masking. Visual processing impairments include an inability to perceive complex visual illusions.
  • Social cognition is concerned with the mental operations needed to interpret, and understand the self and others in the social world. This is also an associated impairment, and facial emotion perception is often found to be difficult. Facial perception is critical for ordinary social interaction.

Subtypes

Paranoid Schizophrenia

• Paranoid schizophrenia usually manifests itself in intense and nonsensical suspicion and the feeling of being followed or watched.
• They will focus on this delusion and become entirely preoccupied with it, sometimes experiencing auditory hallucinations that confirm their suspicions.
• The one positive is that most of the common symptoms of schizophrenia, such as disorganized behavior and speech patterns, are usually not present in those with paranoid schizophrenia.
• I think Schizophrenia is not a simple hemogenous disorder, but a spectrum of disease which could be categorized by some axis such as Elapsed time from start,...

Paranoid Schizophrenia Entity / Miasms

	NVCJD	JE	RBS
Hallucination	+++	+++	+++
Auditory H	+++
Delusion	+++	+++	+++
Psychosis	+++	+++	+++
Altered Pattern of thought	+++	+++	+++

Catatonic Schizophrenia

• An individual with catatonic schizophrenia will either move too much or too little.
• If they are not moving, they will either sit motionlessly and resist any attempts to move them, staying rigid and stationary.
• If they are excessively moving, they will engage in purposeless movement, repeat what others say over and over, and mimic the movements of those around them.
• They may also make strange faces or body contortions, and engage in rocking, waving, or nail-biting.
• The instances of catatonic schizophrenia have decreased of late since these symptoms are mostly the result of untreated schizophrenia.

Catatonic Schizophrenia Entity / Miasms

Rigidity
Sterotypia

5.3 Residual Schizophrenia

• Residual schizophrenics are not currently experiencing any of the more serious symptoms of schizophrenia, including no signs of hallucinations, disorganized speech, or catatonic behaviors. However, they will experience at least two minor symptoms, such as odd beliefs, trouble paying attention, withdrawing from society, and talking less.

5.4 Disorganized Schizophrenia

• Disorganized schizophrenia is primarily distinguished by “disorganized” symptoms such as disorganized speech, behavior, and inappropriate behavior. This can include resisting eye contact, the inability to make facial expressions, incoherence, and trouble beginning or finishing a task.

5.5 Undifferentiated Schizophrenia

• If somebody diagnosed with schizophrenia has trouble classifying themselves into any of the above subtypes but still experience symptoms, they will be labeled as someone with undifferentiated schizophrenia.

6 Schizophrenia Black Box

• If you look at Schizophrenia deeply, you see that Human-being has free will around the axis of self.
• "Free-will" make and support "Self".
• So self is not a meaningful identity without free-will.
• You make yourself by your thinking / behaviors. Probably you imitate someone, then what makes these thinking / Behaviors, yours? Of course your free-will.
• This is your identity, therefore you are caring it Uninterruptedly.

• Free-will did not exist from the beginning, therfore you make it through evolution since you need it.
• It is vital for your survival so anything that threatens it is considered an emergency.
• That's why hallucinations of RBS is so wild, since this virus attack the center of you, which is your self-identity.
• This is the state of Delirium and if it is not solved, it would be push you to the state of Paranoid mania. In this stage the patient have transient Hallucination with or without Delusions.
• The second stage would be Paranoid Schizophrenia. In this stage thought pattern is destroyed.
• In the third stage the patient loose his movement control which is named Catatonic Schizophrenia. Since his movement system is intact, he has purposeless movement which is named Stereotypy or purposeless immobility which is incorrectly named Rigidity.
• The end stage of this sinister story is Hebephrenic Schizophrenia. in this stage the patient enters a persistent disorganizing of will which is the meaning of skhizein= split phrēn= mind.

	NVCJD	RBS	JE
Psychosis	+++	+++	+++
Delusions	+++	+++	+++
Hallucination	+++	+++	+++
Auditory H	+++	---	---
Depression	+++	---	+++
Altered Pattern of thought	---	+++	+++
Behavioral change	+++	+++	+++
Cognition impaired	+++	+++	+++
Memory weakness	+++	+++	+++
Rigidity	---	+++	+++
Sub types	Paranoidal or Disorganized	Catatonic	Catatonic or Disorganized

7 Remedies

Anac

Hyos

Syph