NVCJD, New Variant Creutzfeldt Jakob Disease

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Core

NVCJD focuses on Pulvinar nucleus of Thalamus

  • Visual attention / Impaired concentration
  • Visual salience
  • Social cognition
  • Neglect syndrome / Disorientation = Spatial Confusion
  • Gait disorder /Incoordination


Entities

UMNS


Psychosis

  • Auditory / Visual Hallucination
  • Delusions
  • Behavioral change
  • Agitation, Irritability, Anger, Sleeplessness



  • Dysesthesia , Painful Paresthesia


Ataxia (Maybe)

  • Incoordination
  • Gait abnormalities


Autonomic dysfunction (Maybe)

  • Recent researches suggest that vCJD attack brain from the GI tract autonomic nervous system (Both parasympathetic and sympathetic)[1]
  • Dysarthria (Possibly UMN Dysarthria)
  • Dysphagia
  • Urine Incontinence

Choreathetosis

Diseases

Dementia

  • Disorientation
  • Impaired Cognition
  • Memory; weakness
  • Depression
  • Anxiety

Schizophrenia

  • Psychosis
  • Hallucination, Auditory, Visual
  • Delusion
  • Altered though pattern
  • Behavioral change

Remedies

  1. LACH, BELL
  2. Stram
  3. Crot-c, Carbn-s
  1. Amanda L. Woerman, Gültekin Tamgüney,↵↵Body-first Parkinson’s disease and variant Creutzfeldt–Jakob disease – similar or different?,↵↵Neurobiology of Disease,Volume 164, 2022,