Thrombocytopenia

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Revision as of 10:26, 19 February 2023 by Oldver>Mehrdad (Created page with "=== Clinic === * It is a condition characterized by abnormally low levels of Platelets/ Thrombocytes, in the blood. * It is the most common coagulation disorder * Thrombocytopenia can be contrasted with the conditions associated with an abnormally ''high'' level of platelets in the blood - thrombocythemia (when the cause is unknown), and thrombocytosis (when the cause is known). === Signs / Symptoms === * Petechiae / Purpura * External bleeding, such as nosebleed...")
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Clinic

  • It is a condition characterized by abnormally low levels of Platelets/ Thrombocytes, in the blood.
  • It is the most common coagulation disorder
  • Thrombocytopenia can be contrasted with the conditions associated with an abnormally high level of platelets in the blood - thrombocythemia (when the cause is unknown), and thrombocytosis (when the cause is known).


Signs / Symptoms

  • Petechiae / Purpura
  • External bleeding, such as nosebleeds or bleeding gums


Causes

Decreased production

Abnormally low platelet production may be caused by:

  • Dehydration, vitamin B12 or folic acid deficiency
  • Leukemia, Myelodysplastic syndrome or aplastic anemia
  • Liver failure
  • Sepsis, systemic viral or bacterial infection
  • Leptospirosis
  • Hereditary syndromes

Increased destruction

Other causes

  • Medication-induced
  • Snakebite
  • Lyme disease
  • Thrombocytapheresis (Plateletpheresis)
  • Niemann–Pick disease


Miasms:

DHF