Autonomic neuropathy

Clinic

• AN or AAN is a form of polyneuropathy that affects Autonomic nervous system
• It is a series of entities, most common caused by diabetes mellitus type 1 and 2.
• AN occurs usually alongside other forms of neuropathy, such as sensory neuropathy.
• It is one of dysautonomia causes
• Autoimmune peripheral neuropathies

Types

Urinary bladder conditions

Neurogenic bladder is a broad term used to describe this dysfunction.

• Urinary incontinence
• Urinary retention

Gastrointestinal tract

• Dysphagia
• Abdominal pain
• Nausea, vomiting
• Malabsorption
• Fecal incontinence
• Gastroparesis
• Diarrhea
• Constipation

Cardiovascular system

• Tachycardia, Bradycardia
• Orthostatic hypotension
• Inadequate increase of heart rate on exertion

Respiratory system

• Central sleep apnea
• Hypopnea
• Bradypnea

Nervous system

• Pupillary defect
• Exaggerated hippus
• Dizziness or lightheadedness.

Other areas

• Hypoglycemia unawareness
• Genital impotence
• Sweat disturbances

Causes

Dynamic	Static
Diabetes Parkinson's disease Parkinson's Plus diseases including Multiple system atrophy Lewy body dementia Multiple sclerosis Autoimmune diseases Sjögren syndrome / Sicca Systemic lupus erythematosus Rheumatoid arthritis Celiac disease Guillain–Barré syndrome Autoimmune autonomic ganglionopathy Certain infectious diseases: Lyme disease HIV	Nerves injury certain medications (Chemotherapy) Amyloidosis Paraneoplastic syndrome Certain hereditary disorders Botulism