MTB, Mycobacterium tuberculosis

MTB in brief

• Chilliness, Fatigue. Weight loss. Lethargy,
• Increased night Perspiration, Low-grade Afternoon, Fever, Night aggravation.
• Anorexia.
• Abscess, ulcer, lymph adenopathy
• Mucus membrane respiratory, GI, Genital, eye
• Endocrine involvement

Entities

• Meningitis: Headache, Confusion, Coma, Seizure
• Uveitis, Chorioretinitis
• Otitis media: Ear Pain
• Ulceration: Mouth, Tongue, Esophagus (Odynophagia. Dysphagia), Skin
• Colitis: Rectal pain + Diarrhea
• Lymphadenopathy: Mediastinum, Axilla, Cervical
• Abscess: Abdominal wall, Hepatic; Pancreas, Spleen, Psoas muscle, Prostate
• Mucous membrane inflammation:
  • Bilateral Pleuritis (Pleural effusion),Pleurodynia
  • Peritonitis
  • Cholangitis: Vomiting
  • Pericarditis
  • Conjunctivitis
  • Iritis
  • Keratitis
• Laryngitis: Hoarseness
• Pneumonia: Hemoptysis , Rales, Productive Cough, Dyspnea, Wheezing Respiration
• Arthritis: Arthralgia
• Spondylitis: Paravertebral. Stiffness, Back Pain
• Bone lesions: Osteoporosis, Calcium- Vit-D difficulties

• Dysuria. Frequency

• Genital tuberculosis: Testis (Painful Swelling), Epididymitis, Prostatitis, Oligo spermia, Female infertility

• Eruptions. Nodules.
• General: Chilliness, Fatigue. Weight loss. Lethargy, Increased night Perspiration, Low-grade Afternoon, Fever, Night aggravation. Anorexia.
• Anemia, Leukopenia, Thrombocytopenia, Polycytemia.

• Endocrine involvement: Adrenal insufficiency, diabetes mellitus and calcium-vitamin D abnormalities were the most prevalent and frequently reported endocrine disorders among adult patients with tuberculosis in Africa. other rare endocrine defects are thyroid dysfunction and hypogonadism

Female infertility

• Infertility affects 60–80% of women with Female Genital TB
• It occurs due to distortion or obstruction of the fallopian tubes, intrauterine adhesions causing inadequate endometrial receptivity, or inflammatory destruction of ovarian tissue leading to defective ovarian reserve
• Primary infertility (when pregnancy has never occurred) is more common than secondary infertility and accounts for 66%–85% of infertility.
• Following infertility, the most frequently reported symptoms in women of reproductive age are
  • Menstrual irregularities
  • Nonspecific symptoms such as lower abdominal or pelvic pain and abnormal vaginal discharge
  • Asherman syndrome (intrauterine adhesions alongside infertility and menstrual irregularities
  • In postmenopausal women, FGTB is characterized by postmenopausal bleeding, leukorrhea, and pyometra

Anal tuberculosis

• It is an extremely rare extrapulmonary presentation of MTB
• Less than 1% of the individuals who contract TB manifests as GI TB, and anoperineal TB is much less frequently encountered, 1% of the TB cases of the digestive tract.
• Anal fistula

Related Disease

• Sarcoidosis
• IBD

Remedies

2. HEP, NIT-AC, PHOS
3. Lyc, Psor, Sul, Ars, Merc, Ant-t
4. Tub, Sil, Iod, Canth, Spong, Am-m, Sep, Thuj, Graph