Anosmia

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Clinic

  • Also known as smell blindness, is the loss of the ability to detect one or more smells.
  • Anosmia may be temporary or permanent. It differs from hyposmia, which is a decreased sensitivity to some or all smells.

Causes

  • Inflammation of the nasal mucosa, blockage of nasal passages or
  • Destruction of one temporal lobe.

When anosmia is caused by inflammatory changes in the nasal passageways, it is treated simply by reducing inflammation.

  • It can be caused by chronic meningitis and neurosyphilis that would increase intracranial pressure over a long period of time.
  • Ciliopathy, including ciliopathy due to primary ciliary dyskinesia.
List of causes
Dynamic Dynamic
Peripheral Central Static
Nasal polyps
  • Hypothyroidism
  • Head trauma, damage to the ethmoid bone
  • Tumors of the frontal lobe
  • Antibiotics
  • Hypoglycaemia
  • Exposure to hydrogen sulfide (H 2S) by paralysis of the olfactory nerve.
  • Exposure to a chemical that burns the inside of the nose
  • Radiation therapy to the head and neck
  • Chronic atrophic rhinitis
  • Toxins (especially acrylates, methacrylates and cadmium)
  • Diabetes
  • Chronic obstructive pulmonary disease (COPD)
  • Long term alcoholism
  • Stroke
  • Epilepsy
  • Liver or kidney disease
  • Kallmann syndrome
  • Primary ciliary dyskinesia
  • Post-perfusion syndrome
  • Laryngectomy with permanent tracheostomy
  • Esthesioneuroblastoma is an exceedingly rare cancerous tumor that originates in or near the olfactory nerve. Symptoms are anosmia (loss of sense of smell) often accompanied by chronic sinusitis.
  • Intranasal drug use
  • Aspirin-exacerbated respiratory disease (AERD), also known as Samter's triad
  • Foster Kennedy syndrome
  • Cadmium poisoning
  • Smoking
  • Neurotropic virus
  • Schizophrenia
  • Pernicious anemia
  • Zinc deficiency
  • Bell's Palsy or nerve paralysis and damage
  • Idiopathic intracranial hypertension
  • Suprasellar meningioma
  • Refsum's disease
  • Adrenergic agonists or withdrawal from alpha blockers (vasoconstriction)
  • Sarcoidosis
  • Zinc-based intranasal cold products, including remedies labelled as "homeopathic"
  • Paget's disease of bone
  • Cerebral aneurysm
  • Granulomatosis with polyangiitis
  • Snakebite
  • Idiopathic anosmia (cause cannot be determined)


Miasms

  • COV-19
  • HSV-1, HSV-2 </ref> Landis BN, Vodicka J, Hummel T. Olfactory dysfunction following herpetic meningoencephalitis. J Neurol. 2010 Mar;257(3):439-43. doi: 10.1007/s00415-009-5344-7. Epub 2009 Oct 10. PMID: 19820982.</ref>
  • NVCJD (Ref: REUBER M, AL-DIN ASN, BABORIE A, et al, New variant Creutzfeldt-Jakob disease presenting with loss of taste and smell, Journal of Neurology, Neurosurgery & Psychiatry 2001;71:412-413.
  • CJD (Ref: Sporadic CJD Found in Olfactory Cilia, Medscape)

The Sun is pretty big.[1] The Moon, however, is not so big.[2]

Notes

  1. E. Miller, The Sun, (New York: Academic Press, 2005), 23–25.
  2. R. Smith, "Size of the Moon", Scientific American, 46 (April 1978): 44–46.

Notes