MS, Multiple Sclerosis

Clinic

• MS is a demyelinating autoimmune disease of nervous system.

Specific symptoms:	Related disease	MS types
Double vision / Blindness in one eye Muscle weakness Trouble with sensation Incoordination Cognitive disturbance	GBS Acute disseminated encephalomyelitis Subacute sclerosing panencephalitis	I think MS is an umbrella covering a list of demyelinating disease. I suggest a new classification Considering sign / Symptoms which equals the localization of demyelination. Autonomic Visual Motor Sensory Vestibular Cerebellar

Miasmatic analysis

In order to find appropriate miasm, I need to know series of miasms which could cause Encephalomyelitis. Then the localized involvement could specialized the miasm. ADEM could be a good choice.

MS types	Pathology	Sign / Symptoms	Entities	Miasms	Suggested Remedies
Vestibular MS (49–59%)	Intra-pontine 8th nerve fascicle involvement= Acute Vestibular Syndrome (AVS)	Vertigo, dizziness Imbalance Impaired functional ability, contribute to falls and significant health and social care costs	ADEM Ataxia Vertigo or Dizziness	VZV for vertigo STLE for dizziness	Gels Alum
Autonomic MS	Cardiovascular / Thermoregulatory function during exercise Due to Hypothalamus temperature regulation disorder.	Uhthoff's sign: Agg from higher than usual temperatures Attenuated elevations in blood pressure during exercise can negatively impact blood flow to skeletal muscle. Diminished sweating during exercise	ADEM / SSPE Thermoregulation impaired	RBOL
	Bowel MS: Bowel accidents can also be caused by reduced sensation in back passage, so he dose not recognize the urge to go to the toilet, and reduced control of the muscles at the bottom of his anus.	Constipation due to Decreased or slowed Bowel motility. Hard plug of impacted stool builds up in the back passage, Overflow incontinence: A loose, watery stool can leak out	Constipation Involuntary stool	HSV-1 HSV-2	Alum
	Bladder MS:Urge incontinence (8%): Spastic/ Overactive bladder:	Incontinence: Unable to hold urine Frequency / Urgency Hesitancy / Difficulty in starting urination	ADEM / Brain-stem Incontinence Frequency / Urgency	HTLV-1 STLE	Caust
	Bladder MS: Overflow Bladder that does not empty properly Nocturia	Bladder does not empty properly (retains some urine in it)	ADEM Bladder/Atonia	HSV-1
UMN MS	Corticospinal tract involvement		ADEM Spasticity Paralysis/Weakness: Hyper Reflexia Reflexes, Primitive	HTLV-1 HIV	Arg-n Lat-s Plb Pic-ac
Cerebellar MS			ADEM Tremor Cerebellar Ataxia Dysarthria	CXB VZV	Alum Con
Visual MS	Sudden visual loss		ADEM / SSPE Optic neuritis/Atrophy	EBV WNE HTLV-1 RBOL	Gels Phys
Cognitive MS	40-65 % Cognition skills such as Cognitive miasms: VZV, EBV, HHV-6, CMV, HSV-2, RBOL, HSV-1 Aphasic Miasms: VZV	Memory Attention span Information processing (Decision making, Problem solving) Visual-Spatial Abilities Verbal Fluency: Word-Hunting or mixing words	ADEM / SSPE Cognition Concentration Memory Aphasia	VZV EBV INFL MMP
Painful MS	Central sensitization and second Hyper Stasia	There are two different form first . It seems that both of them have same maiasmatic origin. Central sensitization and sensory MS could be explained commonly.	Hyper Stasia Dysesthesia	HSV-1 HSV-2 HTLV-1	Ox-ac Pic-ac

Related disease

RBD

• Rapid eye movement sleep behavior disorder (RBD) is a parasomnia characterized by brief recurrent episodes of loss of muscle atonia during rapid eye movement sleep, with enacted dreams that cause sleep disruption.
• MS patients have an increased risk compared with the general population to be affected by a sleep disturbance, including RBD. Patients affected, however, uncommonly can present RBD as the first clinical manifestation of MS without other neurologic deficits. These clinical presentations have usually been attributed to inflammatory lesions in the pedunculopontine nuclei, located in the dorsal pons. We present a case of RBD in a 38-year-old woman who was later diagnosed as having MS due to imaging findings and development of focal neurologic deficits. MS should be considered among the differential diagnoses in patients who present with symptoms of RBD, particularly if they are young and female.

Remedies

Prominent Eye Symptoms	Phys	Dim vision, Blurred vision Partial loss of vision Trembling of vision	C30 Pain over orbits, cannot bear to rise eyelids. Spasm of ciliary muscles + Irritability after using eyes.
	Gels After Influenza Optic neuritis Orbital neuralgia In-Coordination/ Imbalance Bladder paralysis Ptosis Eyes Muscles paralysis	Optic neuritis: Blurred/ Foggy / Smoky vision Varying degree of vision loss Dim sighted, pupils dilated and insensible to light. Blurring and discomfort in eyes even after accurately adjusted glasses.	Orbital neuralgia: Pain in the eyes Contraction and twitching of muscles. Ptosis, eyelids heavy, patient can hardly open them with double vision. C200
Difficulty in Balance / Incoordination / Ataxia		Lack of muscle Coordination/ Balance Gait is slow and unsteady. Loss of balance while walking Varying degrees of motor paralysis. Paralysis: Eyes Muscles, throat, larynx, extremities Muscular weakness. Loss of power of muscular control	Intense Dizziness /Drowsiness / Dullness General prostration + Trembling Muscular weakness / Complete relaxation. Cramps in muscles Profuse, clear, watery urine Chilliness Tremulousness. Partial paralysis of bladder
	Alum Locomotor ataxia	Locomotor ataxia Sluggish and staggering gait Numbness and a bandaged feeling in legs. Constipation	C200 Staggers on walking. Spinal degeneration and paralysis of lower limbs Romberg test positive: Tottering and falling on closing the eyes
Numbness, Tingling, Pin/ Needle-like Sensations	Ox-ac Spot pain starting from spine	Extremities are involved in MS. Numbness extends from shoulders to finger tips. Backache with numbness: Pain Drawing/ Sharp / Shooting/ Lancinating / Spot pain starting from spine and extend through limbs.	Muscular prostration: Weakness and coldness in the lower limbs Thinking about pain, agg. Weak trembling Hands / Feet. C30
	Pic-ac Spinal burning	Feel pin and needle pricks in their limbs. Marked Prostration/ Weakness / Tired / Heavy all over the body muscles Spasms from MS	C 30 Worn out persons, both mentally and physically. Burning sensation along the spine. Weakness agg with exertion.
Weakness in Lower Limbs	Con MS + Vertigo Begins in lower limb	MS + muscular weakness, esp lower limbs. Weak and weary legs /Unsteady walk, Sudden loss of strength in walking Difficult gait / Stiffness / Heaviness in legs Weakness in calf muscles, Rigidity in calves Positive Romberg test Trembling of all the limbs esp legs Numbness of fingers and toes. Ms from Grief	C200 Old age problems of Weakness/ Debility Urinary troubles, Weak memory Eye troubles: Dim sighted agg in artificial lights. Paralysis of ocular muscles. Heavy, weary, paralyzed and trembling unsteady hands.
	Arg-n	With softening of spinal cord. (Myelomalacia) Weakness, rigidity, or twisting in calf muscles. Walks and stands unsteadily. Legs stiffness Trembling and numbness of limbs + General debility.	Neurotic effects In-coordination, loss of control /Imbalance Trembling in affected parts Great desire for sweets. Spots before eyes. Eye strain from sewing worse in warm room. Blurred vision.
	Plb Twitching Tremor Hyperesthesia Pain in atrophied muscles	Paralysis of lower limbs. Paralysis of single muscles, chiefly of extensor, forearm or upper limb from canter to periphery. Cannot raise arms, can’t lift anything. Extension is difficult. Partial anesthesia or Excessive hyperesthesia preceded by pain. Twitching/ Tremor / Cramps in calves	C200 Localized neuralgic pains with neuritis. Eyes: Sudden loss of sight after fainting. Paralysis from overexertion of extensor muscles in piano players. Constipation Pain in atrophied muscles + Colic Stinging/ Tearing / Tingling/ Numbness
Spasticity	Lat-s	Spasticity is most marked in the legs. Rigidity, with a spastic gait. Trembling or tottering gait. Cramps in the legs Lower limbs and Gluteal muscles emaciation	C30 MS with spastic paralysis of lower limbs. Reflexes are increased. MS with softening of spinal cord.
	Nat-m	MS with painful contractions of thigh muscle Ankles weak and sprain easily. Coldness of legs with congestion of head, chest and stomach. Eyelid heavy. Ms from Grief	See sparks. Fiery zigzag lines running. Great weakness and emaciation. Psychic causes of diseases and ill effects of grief, fright and anger. Consolation agg
Urinary incontinence	Caust	C 200 Involuntary passage of urine, on coughing , walking, blowing nose or sneezing Urine dribbles or passes slowly. Paralysis of bladder + Involuntary urination on sneezing and coughing. Unsteady walking and easily falling. Weakness and progressive loss of muscular strength, causing paralysis of single organs Ms from Grief	Tearing/ Drawing pains + Severe weakness. Local paralysis: Vocal cords, tongue, eyelids, face, bladder + Single parts of extremities + Dull, tearing pains + Loss of sensation. Impaired vision + Sparks/ Dark spots before eyes. Ptosis + Paralysis of extra ocular muscles. Restless legs at night + Weak ankles. Amel by warmth esp heat of bed.
	Phos	Marked prostration + Trembling + Numbness + Complete paralysis Sensory and motor paralysis from ends of fingers and toes. Weakness and trembling from every exertion. Arms and hands become numb. Can scarcely hold anything.	Black points seem to float before the eyes. Fatigue of eyes and head with hands. Sensitives to external impressions like light, sound, touch and thunders. Ms from Grief
Other remedies	Zinc Cupr Syph Cic

Homeopathic medicines are selected on the basis of symptoms, cause, family history and constitution of the person affected. Considering all these factors any of the above (or some other) homeopathic medicine may be indicated and helpful in a case of Multiple Sclerosis.