MTB, Mycobacterium tuberculosis

MTB in brief

• Chilliness, Fatigue. Weight loss. Lethargy, Anorexia
• Night Perspiration
• Low-grade Afternoon, Fever, Night aggravation
• Abscess, ulcer, lymphadenopathy
• Mucous membrane inflammation: Respiratory, GI, Genital, Eye
• Endocrine involvement
• Genital tuberculosis
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Entities	Sign / Symptoms	Disease
Meningitis	Headache,
	Confusion, Coma, Seizure
Uveitis Chorioretinitis Conjunctivitis Iritis Keratitis
Otitis media	Ear Pain
Ulceration	Mouth, Tongue, Esophagus (Odynophagia. Dysphagia) Skin, Colon	IBD
Colitis	Rectal pain Diarrhea
Lymphadenopathy:	Mediastinum Axilla Cervical
Abscess:	Abdominal wall Hepatic; Pancreas, Spleen Psoas muscle Prostate
Pleuritis	Pleural effusion Pleurodynia Bilateral
Peritonitis
Cholangitis:	Vomiting
Pericarditis
Laryngitis	Hoarseness
Pneumonia	Hemoptysis Rales, Wheezing Productive Cough Dyspnea	Sarcoidosis
Arthritis	Arthralgia
Spondylitis	Paravertebral Back Pain / Stiffness
Bone lesions Osteoporosis	Calcium- Vit-D difficulties
	Dysuria Frequency
Epididymitis Prostatitis	Painful Swelling of Testis Oligo spermia
Female infertility	Hypogonadism
Eruptions. Nodules
Anemia Leukopenia
Thrombocytopenia
Polycytemia
Adrenal insufficiency,
diabetes mellitus
Thyroid dysfunction

Female infertility

• Infertility affects 60–80% of women with Female Genital TB
• It occurs due to distortion or obstruction of the fallopian tubes, intrauterine adhesions causing inadequate endometrial receptivity, or inflammatory destruction of ovarian tissue leading to defective ovarian reserve
• Primary infertility (when pregnancy has never occurred) is more common than secondary infertility and accounts for 66%–85% of infertility.
• Following infertility, the most frequently reported symptoms in women of reproductive age are
  • Menstrual irregularities
  • Nonspecific symptoms such as lower abdominal or pelvic pain and abnormal vaginal discharge
  • Asherman syndrome (intrauterine adhesions alongside infertility and menstrual irregularities
  • In postmenopausal women, FGTB is characterized by postmenopausal bleeding, leukorrhea, and pyometra

Anal tuberculosis

• It is an extremely rare extrapulmonary presentation of MTB
• Less than 1% of the individuals who contract TB manifests as GI TB, and anoperineal TB is much less frequently encountered, 1% of the TB cases of the digestive tract.
• Anal fistula

Related

• IBD

Remedies

2. HEP, NIT-AC, PHOS
3. Lyc, Psor, Sul, Ars, Merc, Ant-t
4. Tub, Sil, Iod, Canth, Spong, Am-m, Sep, Thuj, Graph