HHV-6, Human Herpes Virus 6: Difference between revisions
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* ''[[Encephalitis]]'': '''Irritability, Sleeplessness,''' ''[[Seizure]]'' | * ''[[Encephalitis]]'': '''Irritability, Sleeplessness,''' ''[[Seizure]]'' | ||
* '''[[ | * '''[[Otitis media]]''' | ||
* ''Fulminant'' ''[[Hepatitis remedies|Hepatitis]]'': ''Vomiting, Eructations. '''Diarrhea''''' | * ''Fulminant'' ''[[Hepatitis remedies|Hepatitis]]'': ''Vomiting, Eructations. '''Diarrhea''''' | ||
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=== Related disease === | === Related disease === | ||
* | * [[MS, Multiple Sclerosis|Multiple Sclerosis]] | ||
* | * [[Chronic fatigue syndrome (CFS)|Chronic fatigue syndrome]] | ||
* Atypical lymphocytosis, ''Lymphoproliferative malignancies'' | * Atypical lymphocytosis, ''Lymphoproliferative malignancies'' | ||
* [[Sporadic necrotizing encephalitis]] | |||
=== Researches === | === Researches === | ||
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* The reactivation of HHV-6 in drug-induced hypersensitivity syndrome is not a coincidental phenomenon. HHV-6 reactivation plays an important role in the pathogenesis of drug-induced hypersensitivity syndrome, esp in the latter half of the clinical symptoms. It sometimes leads to the severe complications of drug-induced hypersensitivity syndrome, such as encephalitis and [[Type 1 DM|type 1 diabetes mellitus]]. In conclusion, drug-induced hypersensitivity syndrome is a complex disease composed of drug allergy and human herpesvirus 6. <ref>Hashimoto K, Yasukawa M, Tohyama M. Human herpesvirus 6 and drug allergy. Curr Opin Allergy Clin Immunol. 2003 Aug;3(4):255-60. doi: 10.1097/00130832-200308000-00004. PMID: 12865768.</ref> | * The reactivation of HHV-6 in drug-induced hypersensitivity syndrome is not a coincidental phenomenon. HHV-6 reactivation plays an important role in the pathogenesis of drug-induced hypersensitivity syndrome, esp in the latter half of the clinical symptoms. It sometimes leads to the severe complications of drug-induced hypersensitivity syndrome, such as encephalitis and [[Type 1 DM|type 1 diabetes mellitus]]. In conclusion, drug-induced hypersensitivity syndrome is a complex disease composed of drug allergy and human herpesvirus 6. <ref>Hashimoto K, Yasukawa M, Tohyama M. Human herpesvirus 6 and drug allergy. Curr Opin Allergy Clin Immunol. 2003 Aug;3(4):255-60. doi: 10.1097/00130832-200308000-00004. PMID: 12865768.</ref> | ||
* [[Myocarditis]]: HHV-6 is one of the most important pathogens of viral myocarditis, and is often responsible for sudden death in young adults. A 59-year-old immunocompetent man died of serious lymphocytic myocarditis, and his peripheral blood sample showed HHV-6 DNAemia. <ref>Fatal human herpes virus 6B myocarditis: Postmortem diagnosis of HHV-6B based on CD134<sup>+</sup> T-cell tropism, Department of Legal Medicine, Kyorin University School of Medicine, 6-20-2 Shinkawa, Mitaka-shi, Tokyo 181-8611, Japan</ref> | * [[Myocarditis]]: HHV-6 is one of the most important pathogens of viral myocarditis, and is often responsible for sudden death in young adults. A 59-year-old immunocompetent man died of serious lymphocytic myocarditis, and his peripheral blood sample showed HHV-6 DNAemia. <ref>Fatal human herpes virus 6B myocarditis: Postmortem diagnosis of HHV-6B based on CD134<sup>+</sup> T-cell tropism, Department of Legal Medicine, Kyorin University School of Medicine, 6-20-2 Shinkawa, Mitaka-shi, Tokyo 181-8611, Japan</ref>, <ref>Fatal human herpes virus 6B myocarditis: Postmortem diagnosis of HHV-6B based on CD134<sup>+</sup> T-cell tropism, Department of Legal Medicine, Kyorin University School of Medicine, 6-20-2 Shinkawa, Mitaka-shi, Tokyo 181-8611, Japan</ref> | ||
=== Remedies === | === Remedies === | ||
# | # | ||
#MERC, SUL | #MERC, SUL | ||
# Phos, Bell | # Phos, Bell | ||
# Puls | # Puls | ||
Revision as of 05:20, 13 April 2023
Entities
- Meningitis: Frontal Headache
- Encephalitis: Irritability, Sleeplessness, Seizure
- Fulminant Hepatitis: Vomiting, Eructations. Diarrhea
- Interstitial Pneumonitis: Cough. Wheezing. Rhonchi. Crackle
- Eruptions; macular, papular. Roseola infantum.
- Thrombocytopenia: Hemorrhage: Epistaxis
- Mononucleosis: Cervical lymphadenopathy, Leukopenia
Burning pains. Stitching pains
Coldness of feet.
Eosinophilia, Drug hypersensitivity: Upper respiratory symptoms, Nose Congestion. Coryza, Throat Dryness. Lachrymation, Dim Vision
Related disease
- Multiple Sclerosis
- Chronic fatigue syndrome
- Atypical lymphocytosis, Lymphoproliferative malignancies
- Sporadic necrotizing encephalitis
Researches
- Recent reports offer evidence that HHV-6 reactivation may underlie a characteristic limbic encephalitis syndrome following hematopoietic cell transplant. The cardinal features of this syndrome include memory loss, insomnia, EEG evidence of temporal lobe seizure activity, MRI signal intensity abnormalities of the mesial temporal lobe, and the syndrome of inappropriate release of antidiuretic hormone. Possible associations of HHV-6 with meningoencephalitis, mesial temporal lobe epilepsy, and MS. [1]
- The reactivation of HHV-6 in drug-induced hypersensitivity syndrome is not a coincidental phenomenon. HHV-6 reactivation plays an important role in the pathogenesis of drug-induced hypersensitivity syndrome, esp in the latter half of the clinical symptoms. It sometimes leads to the severe complications of drug-induced hypersensitivity syndrome, such as encephalitis and type 1 diabetes mellitus. In conclusion, drug-induced hypersensitivity syndrome is a complex disease composed of drug allergy and human herpesvirus 6. [2]
- Myocarditis: HHV-6 is one of the most important pathogens of viral myocarditis, and is often responsible for sudden death in young adults. A 59-year-old immunocompetent man died of serious lymphocytic myocarditis, and his peripheral blood sample showed HHV-6 DNAemia. [3], [4]
Remedies
- MERC, SUL
- Phos, Bell
- Puls
- ↑ Gewurz BE, Marty FM, Baden LR, Katz JT. Human herpesvirus 6 encephalitis. Curr Infect Dis Rep. 2008 Jul;10(4):292-9. doi: 10.1007/s11908-008-0048-1. PMID: 18765102.
- ↑ Hashimoto K, Yasukawa M, Tohyama M. Human herpesvirus 6 and drug allergy. Curr Opin Allergy Clin Immunol. 2003 Aug;3(4):255-60. doi: 10.1097/00130832-200308000-00004. PMID: 12865768.
- ↑ Fatal human herpes virus 6B myocarditis: Postmortem diagnosis of HHV-6B based on CD134+ T-cell tropism, Department of Legal Medicine, Kyorin University School of Medicine, 6-20-2 Shinkawa, Mitaka-shi, Tokyo 181-8611, Japan
- ↑ Fatal human herpes virus 6B myocarditis: Postmortem diagnosis of HHV-6B based on CD134+ T-cell tropism, Department of Legal Medicine, Kyorin University School of Medicine, 6-20-2 Shinkawa, Mitaka-shi, Tokyo 181-8611, Japan