Autoimmune Polyendocrine Syndrome: Difference between revisions

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APS-1 may also cause:
APS-1 may also cause:


* Autoimmune hepatitis
* Autoimmune [[hepatitis]]
* [[Hypogonadism]]
* [[Hypogonadism]]
* [[Vitiligo]]
* [[Vitiligo]]
Line 29: Line 29:
* [[Pernicious anemia]]
* [[Pernicious anemia]]
* [[Cataract]]
* [[Cataract]]
* Cerebellar ataxia
* [[Cerebellar ataxia miasms|Cerebellar ataxia]]




== APS-2 ==


===Clinic===
=== APS-1 Entity / Miasm ===
*APS-2 a form of autoimmune polyendocrine syndrome also known as PAS II
*It is the most common form of the polyglandular failure syndromes.
*PAS II is defined as the association between autoimmune [https://wikihomeopathy.com/index.php/Addison's_disease Addison's disease] and either autoimmune thyroid disease, type 1 diabetes, or both.
*It is heterogeneous and has not been linked to one gene.
*APS-II affects women to a greater degree than men.
===Signs and symptoms===
*[https://wikihomeopathy.com/index.php/Hashimoto_thyroiditis Hashimoto thyroiditis]: Nausea, Frequent urination, Palpitations, Weight loss, Anorexia
*Low blood pressure
*Hypoparathyroidism
*Myalgia
*Graves' disease
*Anaemia
*Hypogonadism
*Diabetes mellitus
 
=== Entities / Miasms ===
{| class="wikitable"
{| class="wikitable"
!
!
!EBV
!MTB
!MMP
!B19
!CXB
!HCV
!HCV
!HSV
!HSV
!RBL
!MMP
!EBV
!CMV
|-
|-
|[https://wikihomeopathy.com/index.php/Hashimoto_thyroiditis Hashimoto thyroiditis]
|[[Hepatitis]]
| ++
| +++
|
| +++
|<nowiki>+++</nowiki>
| +++
| +
| +++
|<nowiki>+</nowiki>
| +++
| +++
| +
| +
|-
|-
|[https://wikihomeopathy.com/index.php/Adrenal%20insufficiency Adrenal insufficiency]
|Infertitiy
| +++
|
|
| +++
|
|
|
|
|-
|[[Vitiligo]]
|
|
| +++
|
|
|
|
| ++
| +++
|
|-
|-
|Diabetes Insulin dependent
|[[Atrophic Gastritis entities|Atrophic Gastritis]]
| +++
| +++
|
|
|
| +++
| +++
|
|
| +++
|-
|[[Cataract]]
|
|
|
|
|
|
|
| +++
|-
|-
|Female, Infertility / Oophoritis
|[[Cerebellar ataxia miasms|Cerebellar ataxia]]
|
|
| +++
| +++
| +++
| +++
| +++
|
|
|-
|[[Autoimmune adrenalitis]]
|
|
| ++
|
|
| +
| +++
|}
== APS-2 ==
===Clinic===
*It is the most common form
*It is heterogeneous and has not been linked to one gene.
*It affects women to a greater degree than men.
===Signs and symptoms===
*[[Hashimoto thyroiditis]]: Nausea, Frequent urination, Palpitations, Weight loss, Anorexia
*Low blood pressure
*Hypoparathyroidism
*Myalgia
*Graves' disease
*Anemia
*[[Hypogonadism]]
*Diabetes mellitus
=== APS-2 Entities / Miasms ===
{| class="wikitable"
!
!MTB
!MMP
!EBV
!HCV
|-
|Infertility
| +++
| +++
|
|
|
|
|-
|[[Hashimoto thyroiditis]]
| +++
| +++
| +++
| +++
|-
|-
|Anemia
|Anemia
| +++
| +++
| +++
|
|
| +++
| +++
|<nowiki>+++</nowiki>
|
|
| +++
| +++
|-
|-
|Diabetes mellitus, juvenile
|
|
|
| +++
|
|
|
|
|
|
|
|
|
|}
|}
Note
It seems that APS could be a [[Cluster of disease|COD]].

Revision as of 06:13, 8 April 2023

Types

  • There are two distinct types APS-1 and APS-2
  • APS also named PAS

APS-1

Clinic

  • APS-1causes the dysfunction of multiple endocrine glands due to autoimmunity.
  • It is an inherited in autosomal recessive fashion


Signs and symptoms

  • Chronic mucocutaneous candidiasis
  • Hypoparathyroidism
  • Addison's disease
  • Ectodermal dystrophy (skin, dental enamel, and nails)


APS-1 may also cause:


APS-1 Entity / Miasm

HCV HSV MMP EBV CMV
Hepatitis +++ +++ +++ +++ +++
Infertitiy +++ +++
Vitiligo +++ +++
Atrophic Gastritis +++ +++
Cataract
Cerebellar ataxia +++ +++ +++
Autoimmune adrenalitis ++ + +++


APS-2

Clinic

  • It is the most common form
  • It is heterogeneous and has not been linked to one gene.
  • It affects women to a greater degree than men.

Signs and symptoms

  • Hashimoto thyroiditis: Nausea, Frequent urination, Palpitations, Weight loss, Anorexia
  • Low blood pressure
  • Hypoparathyroidism
  • Myalgia
  • Graves' disease
  • Anemia
  • Hypogonadism
  • Diabetes mellitus

APS-2 Entities / Miasms

MTB MMP EBV HCV
Infertility +++ +++
Hashimoto thyroiditis +++ +++ +++ +++
Anemia +++ +++ +++
Diabetes mellitus, juvenile +++

Note

It seems that APS could be a COD.

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