MTB, Mycobacterium tuberculosis

MTB in brief

• Chilliness, Fatigue. Weight loss. Lethargy, Anorexia
• Night Perspiration
• Low-grade Afternoon, Fever, Night aggravation
• Abscess, ulcer, lymphadenopathy
• Mucous membrane inflammation: Respiratory, GI, Genital, Eye
• Endocrine involvement
• Genital tuberculosis

Entities	Sign / Symptoms	Disease
Meningitis	Headache
	Confusion Coma Seizure
Uveitis Chorioretinitis Conjunctivitis Iritis Keratitis
Otitis media	Ear Pain
Ulceration	Mouth, Tongue Esophagus (Odynophagia. Dysphagia) Skin Colon	IBD
Colitis	Rectal pain Diarrhea
Lymphadenopathy	Mediastinum Axilla Cervical
Abscess	Abdominal wall Hepatic; Pancreas, Spleen Psoas muscle Prostate
Pleuritis	Pleural effusion Pleurodynia Bilateral
Peritonitis
Cholangitis	Vomiting
Pericarditis
Laryngitis	Hoarseness
Pneumonia	Hemoptysis Rales, Wheezing Productive Cough Dyspnea	Sarcoidosis
Arthritis	Arthralgia
Spondylitis	Paravertebral Back Pain / Stiffness
Bone lesions Osteoporosis	Calcium- Vit-D difficulties
	Dysuria Frequency
Epididymitis Prostatitis	Painful Swelling of Testis Oligo spermia
Female infertility	Hypogonadism
Eruptions. Nodules
Anemia Leukopenia
Thrombocytopenia
Polycytemia
Adrenal insufficiency,
diabetes mellitus
Thyroid dysfunction

Female infertility

• Infertility affects 60–80% of women with Female Genital TB
• It occurs due to distortion or obstruction of the fallopian tubes, intrauterine adhesions causing inadequate endometrial receptivity, or inflammatory destruction of ovarian tissue leading to defective ovarian reserve
• Primary infertility (when pregnancy has never occurred) is more common than secondary infertility and accounts for 66%–85% of infertility.
• Following infertility, the most frequently reported symptoms in women of reproductive age are
  • Menstrual irregularities
  • Nonspecific symptoms such as lower abdominal or pelvic pain and abnormal vaginal discharge
  • Asherman syndrome (intrauterine adhesions alongside infertility and menstrual irregularities
  • In postmenopausal women, FGTB is characterized by postmenopausal bleeding, leukorrhea, and pyometra

Anal tuberculosis

• It is an extremely rare extrapulmonary presentation of MTB
• Less than 1% of the individuals who contract TB manifests as GI TB, and anoperineal TB is much less frequently encountered, 1% of the TB cases of the digestive tract.
• Anal fistula

Related

• IBD

Remedies

2. HEP, NIT-AC, PHOS
3. Lyc, Psor, Sul, Ars, Merc, Ant-t
4. Tub, Sil, Iod, Canth, Spong, Am-m, Sep, Thuj, Graph