Vitiligo
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Clinic
- Vitiligo is a disorder that causes the skin to lose its color.
- Specific causes are unknown but studies suggest a link to immune system changes.
- Vitiligo results from the destruction of epidermal melanocytes by autoreactive cytotoxic T cells.
- It seems that vitiligo is a part of Autoimmune disease named APS
- Vitiligo usually associated with diseases like Thyroid abnormality, Pernicious anemia, SLE, diabetes mellitus,IBD, RA, etc.
Signs / Symptoms
- The only sign of vitiligo is the presence of pale patchy areas of depigmented skin
- Rarely itching in the absence of sunburn.
- Patches are initially small, but often grow and change shape.
- They are most prominent on the face, hands, wrists, around body orifices, such as the mouth, eyes, nostrils, genitalia and umbilicus.
- Some lesions have increased skin pigment around the edges.
- They may experience depression and similar mood disorders.
- Koebner phenomenon: Damage to the normal skin frequently results in an area of depigmentation.
- Inflammatory Vitiligo has an erythematous raised border similar to the one sometimes seen in pityriasis versicolour.
Related disease
- Hashimoto's thyroiditis
- Scleroderma
- Rheumatoid arthritis
- Type 1 diabetes mellitus
- Psoriasis
- Addison's disease
- Pernicious anemia
- Alopecia areata
- SLE
- Celiac disease
- Addison's disease
- Autoimmune Polyendocrine Syndrome
Causes
- 6.25-38% of patients have family history for vitiligo
- Vitiligo is considered as an autoimmune disease due to:
- The presence of melanocytes auto-antibodies.
- Associated with other autoimmune disorders.
- Auto-antibodies in first degree relatives of patients
- Associated with HLA – DR4, HLA-DR1.
- Melanocytes Destruction
Rubrics
- Face- Discoloration, White Spot: Ars, Merc, Nat-c
- Genitalia- Spots- Scrotum, White: Merc, Thuj
- Extremities, Discoloration, Upper Limbs, White, in Spot: Apis
- Extremities, Discoloration, Thigh, White, in Spot: Calc
- Extremities, Discoloration, Thigh, White Spot: Calc.
- Extremities, Discloration, Ankle, White, in Spot: Calc.
- Extremities, Discloration, Foot, White In Spot: Apis
- Skin, Discoloration, White, Spot: alum, am-c, ars, aur, berb, calc, carb-an, coca, merc, nat-c, nit-ac, phos, sep, sil, sulph.
Remedies
Banerji protocols | |
|---|---|
| Ars C200, two dose daily for 3 month
If fail:
| |
| Second line | Ars-s-f 6X, two doses daily for 3 month |
Nat-m
- Greasy/ Oily esp on hairy parts.
- Dry eruptions esp on the margins of the hairy scalp and bends of points
- Skin-raw, red, inflamed,
Nit-ac
- Zig-zag, irregular edges, base look like raw flesh.
- Exuberant granulations,
- Forehead Papules: Large jagged, Bleeds on washing
- Sensitive splinter like pains
- Agg: Evening, night, cold climate also in hot weather.
Ars-s-f
- Leucoderma and squamous syphilitic diseases.
- Sciatica and pain around the knee.
- Associated with sense of needle pricks from within outwards in the chest and esp right side also on forehead
Ars
- Skin oversensitive, suppressed eruptions.
- Brownish white spots in skin.
- White patches; dry, rough skin.
Sep
- Delicate skin
Sil
- Skin is delicate, pale, and waxy; a tendency to excessive perspiration.
Sul
Thuj
- Unhealthy skin; brown or brownish white spots here and there
- AMMI VISNAGA – Relieves issues of Vitiligo and reduces associated anxiety. Associated with treatment of spasmodic bodily movements and in the treatment of angina pectoris.
- PSOROLIA COR – It helps in the treatment of Leukoderma, Leprosy and skin diseases. It is also helpful for treating the scorpion sting and snake bites as it has antibacterial and antioxidant properties.