Anxiety

Clinic

• Anxiety is an entity which contain sign/symptoms such as Uneasiness / Worry/ Palpitation / Hyper hydrosis / Mouth dryness
• Its underlying mechanism is Sympathetic hyperactivity.

Anxiety vs. Fear

• Both are entities, differentiating from their qualities as below.

Four main domains	Fear	Anxiety
Duration of emotional experience	Short	Long
Temporal focus	Present	Futute
Specificity of the threat	Specific	Diffuse
Motivated direction	Escape	Additional associated cognitive activity

Neuroanatomy

• Amygdala (which regulates emotions like anxiety and fear, stimulating the HPA axis and sympathetic nervous system). People who have anxiety tend to show high activity in response to emotional stimuli in the amygdala. Some writers believe that excessive anxiety can lead to an overpotentiation of the limbic system (which includes the amygdala and nucleus accumbens), giving increased future anxiety, but this does not appear to have been proven.
• Hippocampus (which is implicated in emotional memory along with the amygdala)

• Research upon adolescents who as infants had been highly apprehensive, vigilant, and fearful finds that their nucleus accumbens is more sensitive than that in other people when deciding to make an action that determined whether they received a reward. This suggests a link between circuits responsible for fear and also reward in anxious people. As researchers note, "a sense of 'responsibility', or self-agency, in a context of uncertainty (probabilistic outcomes) drives the neural system underlying appetitive motivation (i.e., nucleus accumbens) more strongly in temperamentally inhibited than noninhibited adolescents".

The gut-brain axis

• The microbes of the gut can connect with the brain to affect anxiety. Gut microbes such as Bifidobacterium and Bacillus produce GABA and dopamine, respectively.
• Another key pathway is HPA axis. The microbes can control the levels of cytokines in the body, and altering cytokine levels creates direct effects on areas of the brain such as the hypothalamus, the area that triggers HPA axis activity.
• HPA axis regulates production of cortisol. When HPA activity spikes, cortisol levels increase, processing and reducing anxiety in stressful situations.

Remedies

	Mind	/Physical /General Characters	Modalities	Fear of	Disease
Acon	Great Anxiety / Excitement /Hasty His thoughts are coming from stomach Tendency to start at everything Intense, sudden	Dry skin, dry mouth Fast heartbeat Extremely restless: Tosses about in agony, Must change his position often.		Music is unbearable Future Going out Crowd Crossing street	Panic Fear PTSD
Arg-n	Anxiety due to uncertainty Always in Hurry. Time passes too slowly Sad/ Melancholic Forgetfulness / Dull Anxiety makes the patient to walk fast Impulsive/ Impulse to jump, when in a high place.	Digestive disturbance, like diarrhea Sweets cravings but agg	Sweets agg	Face with strangers. Looking at high places Crossing corners of street, Death Anticipation Anxiety	Claustrophobia Hypochondriasis
Ars	Fastidious/ Suspicious They Control their anxiety to prevent being criticized by others. Sad/ Hopeless of recovery Suicidal tendencies / Weary of life/ Impulse to suicide	Often feel cold Weak: Always moving from one place to another, Even physically too weak to move		Loneliness Darkness Being imperfect About money As if he will die soon Incurable disease.	OCD
Calc	Evening anxiety + Restlessness + Palpitation + Mental / Memory weakness (Inability to prolonged mental exertion, difficult thinking, Confusion, Misplacing of words, Indolence). Irritable/ Obstinate/ Sad/ Inclined to weep Horrible dreams Startled at every noise. Prolonged application to business Prolonged worry or anxiety		Evening	Breaking out of any safe routine/ plans. Like Ars Difficulty in going with the flow Insanity/ Loss of reason Death/ Consumption Misfortune / Alone Excitement of emotions.
Gels	Timid/ Feelings of inadequacy They often desire solitude and avoid insistent pressure from other people.	Shaky Vulnerable to fainting		Anxiety due to fright, fear, Exciting news Examination or interview etc Avoid crowds or public speaking	Agoraphobia Stage fright
Kali-ars	Health-based anxiety include hypochondria Excessive grooming Racing thoughts	Feeling cold Difficulty sleeping		Death or dying Heart attacks	Panic attacks Hypochondriasis
Kali-p	Anxiety from having too much to do or increased ambitions Vulnerable to stress or becoming overwhelmed.		Physical complication of anxiety
Phos	Difficult concentration when anxious: Scattered / Difficult time focusing or getting things done Social people with anxiety			Anxiety of being approved in social circles or from romantic partners
Sul	Irritable, impatient of others, selfish, easily excited and offended. Suspicious and mentally depressed. Always tired, occasionally restlessness and hasty. Anxiety with Fainting spells, Profuse sweating, / Agg in the morning.	Opposite states: Forgetful/ Confused / Absent minded /Aversion to Mental/ Physical efforts. Overambitious, Day-dreams, boaster. Or Always in dreams, delusions, thinks rags to be beautiful things. He is a ragged philosopher, very unclean, does not care for neatness. There is no need of cleanliness. Aversion to bathing			Depression
Borx	Children wake suddenly, screaming and grasping sides of cradle without apparent cause. Excessive nervous, easily frightened by slightest noise or an unusual sharp sound, a cough, a sneeze, cry, lighting a match etc.	Fidgetiness and nervousness. Patient becomes nauseated and excitable after mental exertion or in anxiety.	Worse till 11 p.m. Upward or Downward motion Slightest noise	Falling / Going in elevator Anxious about trifles, Easily frightened Fear of falling when rocking, dancing, singing.	Night terrors
Lyc	Lack self-confidence (Similar to Gels, Sil)		4-8 pm	Speaking in public but they hide it well by talking loudly or loquacity	Stage fright
Puls	Childlike anxiety They need lots of reassurance and support from others to feel better.
Sil	Lack self-confidence (Similar to Gels, Lyc) Fear of being the center of attention They tend to become workaholics to palliate their fears.		Occupation amel	Experiencing new things	Stage fright
Stram	Dark thoughts while awake Their imaginations agg their anxiety Scared by thoughts of Monsters/ Mysterious figures			Dark Being alone	Night terrors Nightmares Bed wetting Stammering
Ign	Very sensitive Anxiety from Grief or Loss or Mental shock Moving from laughter to tears, Alteration of opposite mental states. Absent-minded, aversion to company / Weeps and broods in solitude		Hysteria from disappointment Patient weeps, laughs, shrieks jerks and twitches Seizure Faint Unable to control her Emotions /Excitement		Mood swings Depression Hysteria Seizure Syncope
Anac	Dullness / Sluggishness of mind /Memory impaired / Sudden loss of memory / Absent mindedness Suspicious about everything around him Lack of confidence in himself and others Very easily offended Irresistible desire to curse and swear, Abusive Aversion to work, indolence Thinks he is possessed of two wills, one commanding to do what other forbids Hallucinations that a demon sits on one shoulder and an angel on the other Feels he is double, Mind -Body separation.		Eating amel All complaints are worse from mental exertion. Anxious while walking, as if someone is pursuing him		Schizophrenia Hallucinations Delusion Psychosis
Bry	Hazy / Confused. He sleeps frequently, while his eyes are closed, he sees people who are not in room. Mild type of delirium first during sleep, and later on during waking hours. He wants to go home as he thinks he is away from home He wants something but do not know what he wants, desires things which cannot be had, which are refused when offered.			Anxious about business, even when seriously ill Talks incoherently, about Business affairs/ Events of recent happening,	Delirium
Caust	Full of apprehension, Melancholy, Complaining, Hopeless, Foreboding. Prone to fits of anger, startled easily Least things make him peevish. Forgetful/ Taciturn / Restless, esp at night. Always anticipating some dreadful events Lack of mental balance. Hysteria, loses her control of herself, esp at night. Sympathetic for suffering of others			Mental symptoms due to suppression of skin eruptions. Ailments from thinking about them.	Hysteria

Small Remedies

Cact: Very anxious and restless and screams in pain.